(Q21195193)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

19

Hallgeir Rui

Hallgeir

Rui

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Amy R Peck

1

Amy R

Peck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Agnieszka K Witkiewicz

2

Agnieszka K

Witkiewicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Chengbao Liu

3

Chengbao

Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Alexander C Klimowicz

4

Alexander C

Klimowicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Ginger A Stringer

5

Ginger A

Stringer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Edward Pequignot

6

Edward

Pequignot

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Boris Freydin

7

Boris

Freydin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Ning Yang

8

Ning

Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Adam Ertel

9

Adam

Ertel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Thai H Tran

10

Thai H

Tran

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Melanie A Girondo

11

Melanie A

Girondo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Anne L Rosenberg

12

Anne L

Rosenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Jeffrey A Hooke

13

Jeffrey A

Hooke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Albert J Kovatich

14

Albert J

Kovatich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Craig D Shriver

15

Craig D

Shriver

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

David L Rimm

16

David L

Rimm

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Anthony M Magliocco

17

Anthony M

Magliocco

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Terry Hyslop

18

Terry

Hyslop

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

4 October 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

published in

Breast Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

R130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers

9 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Signal transducer and activator of transcription 5A/B in prostate and breast cancers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Truncated p110 ERBB2 induces mammary epithelial cell migration, invasion and orthotopic xenograft formation, and is associated with loss of phosphorylated STAT5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Negative cross talk between NFAT1 and Stat5 signaling in breast cancer.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Standardization of estrogen receptor measurement in breast cancer suggests false-negative results are a function of threshold intensity rather than percentage of positive cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

PTP1B suppresses prolactin activation of Stat5 in breast cancer cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Mechanisms of endocrine resistance in breast cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Breast cancer prognostic classification in the molecular era: the role of histological grade

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Stat5 promotes survival of mammary epithelial cells through transcriptional activation of a distinct promoter in Akt1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Nuclear IRS-1 predicts tamoxifen response in patients with early breast cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

A novel role for signal transducer and activator of transcription 5b (STAT5b) in beta1-integrin-mediated human breast cancer cell migration

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Reciprocal effects of STAT5 and STAT3 in breast cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

In vivo identification of novel STAT5 target genes

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Endpoints in adjuvant treatment trials: a systematic review of the literature in colon cancer and proposed definitions for future trials

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

The retinoblastoma tumor suppressor modifies the therapeutic response of breast cancer

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Ultrahigh density microarrays of solid samples

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Signal transducer and activator of transcription-5 activation and breast cancer prognosis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

A non-functional retinoblastoma tumor suppressor (RB) pathway in premenopausal breast cancer is associated with resistance to tamoxifen

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

The Janus kinase 2 is required for expression and nuclear accumulation of cyclin D1 in proliferating mammary epithelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Automated quantitative analysis (AQUA) of in situ protein expression, antibody concentration, and prognosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Stat5a is mandatory for adult mammary gland development and lactogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Loss of Stat5a delays mammary cancer progression in a mouse model.

30 May 2018

1 reference

Defining the role of prolactin as an invasion suppressor hormone in breast cancer cells.

21 January 2018

1 reference

Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers

21 January 2018

1 reference

Stat5 expression predicts response to endocrine therapy and improves survival in estrogen receptor-positive breast cancer.

21 January 2018

1 reference

Possible role of Stat5a in rat mammary gland carcinogenesis

21 January 2018

1 reference

Automated subcellular localization and quantification of protein expression in tissue microarrays.

21 January 2018

1 reference

Basal activation of transcription factor signal transducer and activator of transcription (Stat5) in nonpregnant mouse and human breast epithelium

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

PRL activates the cyclin D1 promoter via the Jak2/Stat pathway.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4053108

STAT 5a expression in various lesions of the breast

29 November 2018

1 reference

12 December 2020

Do we need better prognostic factors in node-negative breast cancer? Pro:

1 reference

12 December 2020

Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis

1 reference

12 December 2020

Functional rescue of Stat5a-null mammary tissue through the activation of compensating signals including Stat5b

1 reference

12 December 2020

Tamoxifen in the treatment of breast cancer

1 reference

12 December 2020

Lack of prognostic significance of histological grade in node-negative invasive breast carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1186/BCR3328

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 March 2020

1016865309

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23036105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036105%20AND%20SRC:MED&resulttype=core&format=json