(Q21195205)

English

CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen

scientific article

In more languages

Statements

scholarly article

0 references

CYP2D6 gene variants: association with breast cancer specific survival in a cohort of breast cancer patients from the United Kingdom treated with adjuvant tamoxifen (English)

0 references

0 references

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

object named as

Helena M Earl

11

author given names

Helena M

author last names

Earl

1 reference

Dimensions Publication ID

17 August 2022

object named as

Alison M Dunning

12

author given names

Alison M

author last names

Dunning

1 reference

Dimensions Publication ID

17 August 2022

Paul D P Pharoah

13

object named as

Paul D P Pharoah

author given names

Paul DP

author last names

Pharoah

1 reference

Dimensions Publication ID

17 August 2022

object named as

Carlos Caldas

14

author given names

Carlos

author last names

Caldas

1 reference

Dimensions Publication ID

17 August 2022

4

author given names

Radka

author last names

Platte

object named as

Radka Platte

1 reference

Dimensions Publication ID

17 August 2022

8

author given names

Mitul

author last names

Shah

object named as

Mitul Shah

1 reference

Dimensions Publication ID

17 August 2022

author name string

Jean E Abraham

1

author given names

Jean E

author last names

Abraham

1 reference

Dimensions Publication ID

17 August 2022

Mel J Maranian

2

author given names

Mel J

author last names

Maranian

1 reference

Dimensions Publication ID

17 August 2022

Kristy E Driver

3

author given names

Kristy E

author last names

Driver

1 reference

Dimensions Publication ID

17 August 2022

Bolot Kalmyrzaev

5

author given names

Bolot

author last names

Kalmyrzaev

1 reference

Dimensions Publication ID

17 August 2022

Caroline Baynes

6

author given names

Caroline

author last names

Baynes

1 reference

Dimensions Publication ID

17 August 2022

Craig Luccarini

7

author given names

Craig

author last names

Luccarini

1 reference

Dimensions Publication ID

17 August 2022

Susan Ingle

9

author given names

Susan

author last names

Ingle

1 reference

Dimensions Publication ID

17 August 2022

David Greenberg

10

author given names

David

author last names

Greenberg

1 reference

Dimensions Publication ID

17 August 2022

language of work or name

0 references

publication date

2010

0 references

Breast Cancer Research

0 references

12

0 references

4

0 references

R64

0 references

Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

19 March 2017

Efficiency and power in genetic association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

19 March 2017

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

7 April 2017

Whole-genome patterns of common DNA variation in three human populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

7 April 2017

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

7 April 2017

Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Association between CYP2D6 polymorphisms and outcomes among women with early stage breast cancer treated with tamoxifen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Genotype-guided tamoxifen therapy: time to pause for reflection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Prevalent cases in observational studies of cancer survival: do they bias hazard ratio estimates?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Impaired tamoxifen metabolism reduces survival in familial breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Detection of genotyping errors by Hardy-Weinberg equilibrium testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

12 September 2017

Metabolites of tamoxifen in animals and man: Identification, pharmacology, and significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

27 September 2017

A model citizen? Is tamoxifen more effective than aromatase inhibitors if we pick the right patients?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

30 May 2018

Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

19 June 2018

Pharmacogenomics of tamoxifen and aromatase inhibitors

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Polymorphism in the CYP2D6 Tamoxifen-Metabolizing Gene Influences Clinical Effect but Not Hot Flashes: Data From the Italian Tamoxifen Trial

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Genetic polymorphisms of CYP2D6 10 and CYP2C19 2, 3 are not associated with prognosis, endometrial thickness, or bone mineral density in Japanese breast cancer patients treated with adjuvant tamoxifen

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Modification of tamoxifen response: what have we learned?

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Evaluating and improving power in whole-genome association studies using fixed marker sets.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

CYP2D6 genotyping strategy based on gene copy number determination by TaqMan real-time PCR.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

REporting recommendations for tumor MARKer prognostic studies (REMARK).

1 reference

https://api.crossref.org/works/10.1186%2FBCR2629

21 January 2018

Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949659

29 November 2018

Progression-free survival remains debatable endpoint in cancer trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen-receptor binding and biologic activity of tamoxifen and its metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacogenetics of sparteine and debrisoquine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of 4-hydroxy-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a new variant CYP2D6 allele lacking the codon encoding Lys-281: possible association with the poor metabolizer phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human CYP2D6 and mouse CYP2Ds: organ distribution in a humanized mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of CYP2D6 genotypes predictive of tamoxifen pharmacokinetics in metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20731819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/BCR2629

0 references

Dimensions Publication ID

0 references

0 references

0 references

ResearchGate publication ID

0 references

Springer Nature article ID

10.1186/bcr2629

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21195205&oldid=1832488440"