(Q21560953)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

1 reference

9

Rima Kaddurah-Daouk

Rima

Kaddurah-Daouk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2

Steve Rozen

Steve

Rozen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

6

James R Burke

James R

Burke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Xianlin Han

1

Xianlin

Han

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Stephen H Boyle

3

Stephen H

Boyle

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Caroline Hellegers

4

Caroline

Hellegers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Hua Cheng

5

Hua

Cheng

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Kathleen A Welsh-Bohmer

7

Kathleen A

Welsh-Bohmer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

P Murali Doraiswamy

8

P Murali

Doraiswamy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

11 July 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

e21643

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

8 February 2020

copyright license

start time

11 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Lipidomics reveals a remarkable diversity of lipids in human plasma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Vascular risk factors and dementia: how to move forward?

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Alkaline methanolysis of lipid extracts extends shotgun lipidomics analyses to the low-abundance regime of cellular sphingolipids

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Shotgun lipidomics of phosphoethanolamine-containing lipids in biological samples after one-step in situ derivatization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Statistical significance for genomewide studies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Forecasting the global burden of Alzheimer’s disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Toward fingerprinting cellular lipidomes directly from biological samples by two-dimensional electrospray ionization mass spectrometry

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 1.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Metabolomic differences in heart failure patients with and without major depression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Opioid use affects antioxidant activity and purine metabolism: preliminary results

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

The neuropathology of older persons with and without dementia from community versus clinic cohorts

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Systematic analysis of choline-containing phospholipids using multi-dimensional mass spectrometry-based shotgun lipidomics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Metabolomic analysis and signatures in motor neuron disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Microfluidics-based electrospray ionization enhances the intrasource separation of lipid classes and extends identification of individual molecular species through multi-dimensional mass spectrometry: development of an automated high-throughput plat

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Serum sphingomyelins and ceramides are early predictors of memory impairment

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Metabolomics: a global biochemical approach to drug response and disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Metabolomic mapping of atypical antipsychotic effects in schizophrenia.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Metabonomics in pharmaceutical R&D.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Alterations in lipid homeostasis of mouse dorsal root ganglia induced by apolipoprotein E deficiency: a shotgun lipidomics study

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Ceramides in insulin resistance and lipotoxicity

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Lipid alterations in the earliest clinically recognizable stage of Alzheimer's disease: implication of the role of lipids in the pathogenesis of Alzheimer's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Lipid raft composition modulates sphingomyelinase activity and ceramide-induced membrane physical alterations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Mixed brain pathologies account for most dementia cases in community-dwelling older persons

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

A preliminary metabolomic analysis of older adults with and without depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Metabolomic profiling to develop blood biomarkers for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Factors influencing the electrospray intrasource separation and selective ionization of glycerophospholipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Characterization and direct quantitation of ceramide molecular species from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Brain membrane phospholipid alterations in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Association of ceramides in human plasma with risk factors of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021643

Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II).

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3136924

Apolipoprotein E and Alzheimer's disease

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21779331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasma sphingomyelin and subclinical atherosclerosis: findings from the multi-ethnic study of atherosclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21779331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sphingomyelin levels in the plasma membrane correlate with the activation state of muscle satellite cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21779331

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0021643

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

ADS bibcode

2011PLoSO...621643H

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21779331%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

21779331

2 references