Wikidata

(Q21986017)

English

Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

mammalian protein found in Mus musculus

  • PPAR-gamma coactivator 1-alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • Ppargc1a
In more languages

Statements

molecular function
protein binding
determination method
IPI
12 references
retrieved
14 February 2019
stated in
Transcriptional control of brown fat determination by PRDM16
GOA
curator
UniProt
UniProt protein ID
O70343
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism
GOA
curator
UniProt
UniProt protein ID
O70343
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway
GOA
curator
UniProt
UniProt protein ID
O70343
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
GOA
curator
UniProt
UniProt protein ID
O70343
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
IRF4 is a key thermogenic transcriptional partner of PGC-1α
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
retrieved
14 February 2019
stated in
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IPI
cell component
biological process
positive regulation of transcription by RNA polymerase II
determination method
IBA
IEA
IGI
IMP
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
ISO
retrieved
14 February 2019
stated in
PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IMP
retrieved
14 February 2019
stated in
RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IGI
retrieved
14 February 2019
stated in
Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70343
determination method
IBA

Identifiers

 
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