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Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
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scholarly article
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PubMed
PubMed ID
20661474
retrieved
25 January 2017
title
Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis
(English)
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
main subject
Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
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GOA release 2020-03-11
mitochondrion
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inferred from title
author name string
Xingxing Kong
series ordinal
1
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PubMed
PubMed ID
20661474
retrieved
25 January 2017
Rui Wang
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Yuan Xue
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Xiaojun Liu
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Huabing Zhang
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Yong Chen
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Fude Fang
series ordinal
7
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
Yongsheng Chang
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
language of work or name
English
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publication date
22 July 2010
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PubMed
PubMed ID
20661474
retrieved
25 January 2017
published in
PLOS One
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stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
volume
5
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stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
page(s)
e11707
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stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
issue
7
1 reference
stated in
PubMed
PubMed ID
20661474
retrieved
25 January 2017
copyright license
Creative Commons Attribution 4.0 International
start time
22 July 2010
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
1 reference
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PubMed Central
reference URL
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19 March 2017
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
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PubMed Central
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19 March 2017
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Superoxide activates mitochondrial uncoupling proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Cloning and characterization of two mouse genes with homology to the yeast Sir2 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
19 March 2017
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
A simplified system for generating recombinant adenoviruses
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Identification of a new class of steroid hormone receptors
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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19 March 2017
Mitochondria, oxidants, and aging
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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7 April 2017
Sirtuins in mammals: insights into their biological function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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7 April 2017
Metabolic control through the PGC-1 family of transcription coactivators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
7 April 2017
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
7 April 2017
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
7 April 2017
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
7 April 2017
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
7 April 2017
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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7 April 2017
Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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7 April 2017
Regulation of mitochondrial biogenesis during myogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Peroxisome proliferator-activated receptor gamma coactivator-1alpha enhances antiproliferative activity of 5'-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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29 September 2017
A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Sirtuins: critical regulators at the crossroads between cancer and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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29 September 2017
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
PGC-1alpha coactivates PDK4 gene expression via the orphan nuclear receptor ERRalpha: a mechanism for transcriptional control of muscle glucose metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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29 September 2017
Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Primary hepatocyte culture in collagen gel mixture and collagen sandwich
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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29 September 2017
PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
29 September 2017
To ERR in the estrogen pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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29 September 2017
PGC-1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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2 June 2018
Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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27 November 2018
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
27 November 2018
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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27 November 2018
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
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27 November 2018
Specific gene inhibition by adenovirus-mediated expression of small interfering RNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2908542
retrieved
27 November 2018
Identifiers
DOI
10.1371/JOURNAL.PONE.0011707
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2015205
ADS bibcode
2010PLoSO...511707K
0 references
OpenCitations bibliographic resource ID
2015205
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2015205
PMCID
2908542
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2015205
PubMed ID
20661474
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2015205
ResearchGate publication ID
45367079
0 references
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