(Q22010032)

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Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329152%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329152%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

crystal structure

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Glutathione S-transferase alpha 4

1 reference

GOA release 2020-03-11

protein homodimerization activity

1 reference

GOA release 2020-03-11

1 reference

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5

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J A Tainer

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J A

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Tainer

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8 December 2019

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C M Bruns

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C M

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Bruns

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8 December 2019

I Hubatsch

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I

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Hubatsch

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8 December 2019

M Ridderström

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M

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Ridderström

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8 December 2019

B Mannervik

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B

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Mannervik

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8 December 2019

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1 May 1999

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8 December 2019

Journal of Molecular Biology

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8 December 2019

288

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8 December 2019

427-439

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8 December 2019

3

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8 December 2019

Amino acid residue 104 in an alpha-class glutathione S-transferase is essential for the high selectivity and specificity of the enzyme for 4-hydroxynonenal

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

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Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

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Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

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Glutathione S-transferase 8-8 is localized in smooth muscle cells of rat aorta and is induced in an experimental model of atherosclerosis

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

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Isolation and characterization of the human glutathione S-transferase A2 subunit gene

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Rat glutathione transferase 8-8, an enzyme efficiently detoxifying 4-hydroxyalk-2-enals

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Human glutathione S-transferases

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

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Nucleotide sequence of class-alpha glutathione S-transferases from chicken liver

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

An evolutionary approach to the design of glutathione-linked enzymes.

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stress

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

[33] AMoRe: An automated molecular replacement program package

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Glubodies: randomized libraries of glutathione transferase enzymes

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-activity relationships of 4-hydroxyalkenals in the conjugation catalysed by mammalian glutathione transferases

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a novel glutathione S-transferase isoenzyme from mouse lung and liver having structural similarity to rat glutathione S-transferase 8-8.

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

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Cloning and expression of a chick liver glutathione S-transferase CL 3 subunit with the use of a baculovirus expression system

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Nomenclature for human glutathione transferases

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and heterologous expression of cDNA encoding class Alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Low density lipoprotein undergoes oxidative modification in vivo

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

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The high activity of rat glutathione transferase 8-8 with alkene substrates is dependent on a glycine residue in the active site

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Mouse glutathione S-transferase Ya subunit: gene structure and sequence

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Curcumin protects against 4-hydroxy-2-trans-nonenal-induced cataract formation in rat lenses

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Improved Fourier coefficients for maps using phases from partial structures with errors

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessment of phase accuracy by cross validation: the free R value. Methods and applications

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

The free radical theory of aging matures

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1006%2FJMBI.1999.2697

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutathione transferases and cancer

1 reference

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7 January 2021

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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