(Q22061805)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

Artemisinin and a series of novel endoperoxide antimalarials exert early effects on digestive vacuole morphology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

0 references

0 references

0 references

1 reference

2

Thomas D Avery

Thomas D

Avery

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

3

Eric Hanssen

Eric

Hanssen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Maria del Pilar Crespo

1

Maria

del Pilar Crespo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Emma Fox

4

Emma

Fox

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Tony V Robinson

5

Tony V

Robinson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Peter Valente

6

Peter

Valente

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Dennis K Taylor

7

Dennis K

Taylor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Leann Tilley

8

Leann

Tilley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

15 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

Antimicrobial Agents and Chemotherapy

8 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

98-109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

Yeast model uncovers dual roles of mitochondria in action of artemisinin

8 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

The benefits of artemisinin combination therapy for malaria extend beyond the individual patient

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Genome sequence of the human malaria parasite Plasmodium falciparum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

A single amino acid residue can determine the sensitivity of SERCAs to artemisinins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Identification of an antimalarial synthetic trioxolane drug development candidate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinins target the SERCA of Plasmodium falciparum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Prospects for the treatment of drug-resistant malaria parasites.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

New developments in synthetic peroxidic drugs as artemisinin mimics

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Primaquine synergises the activity of chloroquine against chloroquine-resistant P. falciparum.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinin-based combination therapies (ACTs): best hope for malaria treatment but inaccessible to the needy!

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinins: activities and actions

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Antimalarial drug resistance, artemisinin-based combination therapy, and the contribution of modeling to elucidating policy choices

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Synthetic peroxides as antimalarials

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

An Over Four Millennium Story Behind Qinghaosu (Artemisinin)-A Fantastic Antimalarial Drug from a Traditional Chinese Herb

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinin: mechanisms of action, resistance and toxicity

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Malaria: new chemotherapeutic peroxide drugs

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

From mechanistic studies on artemisinin derivatives to new modular antimalarial drugs

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Why artemisinin and certain synthetic peroxides are potent antimalarials. Implications for the mode of action

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Possible modes of action of the artemisinin-type compounds.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Synergy between two calcium channel blockers, verapamil and fantofarone (SR33557), in reversing chloroquine resistance in Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Variations in frequencies of drug resistance in Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Identification of isolate-specific proteins on sorbitol-enriched Plasmodium falciparum infected erythrocytes from Gambian patients

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Averting a malaria disaster in Africa--where does the buck stop?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Antimalarial quinolines and artemisinin inhibit endocytosis in Plasmodium falciparum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Novel endoperoxide antimalarials: synthesis, heme binding, and antimalarial activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Relationship of chloroquine-induced redistribution of a neutral aminopeptidase to hemoglobin accumulation in malaria parasites

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Morphologic effects of artemether on Plasmodium falciparum in Aotus trivirgatus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Qinghaosu-induced changes in the morphology of Plasmodium inui.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Ultrastructure of Plasmodium falciparum "in vitro". II. Morphological patterns of different quinolines effects

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

A Method for Testing for Synergy with Any Number of Agents

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Chemical kinetics and aqueous degradation pathways of a new class of synthetic ozonide antimalarials

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Antimalarial treatment with artemisinin combination therapy in Africa

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

"Tethered" Ru(II) catalysts for asymmetric transfer hydrogenation of ketones.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Ring-opening of unsymmetrical 1,2-dioxines using cobalt(II) salen complexes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Medicinal chemistry: a worthy adversary for malaria

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Malaria: to kill a parasite

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Base- and Co(II)-catalyzed ring-opening reactions of perhydrooxireno[2,3-d][1,2]dioxines: an efficient route to 4-hydroxy-2,3-epoxy-ketones

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Illumination of the malaria parasite Plasmodium falciparum alters intracellular pH. Implications for live cell imaging.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

First examples of the catalytic asymmetric ring-opening of meso 1,2-dioxines utilising cobalt(II) complexes with optically active tetradentate Schiff base ligands: formation of enantio-enriched cyclopropanes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Radical mechanism of action of the artemisinin-type compounds

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2223901

Artemisinin enhances heme-catalysed oxidation of lipid membranes

29 November 2018

1 reference

12 December 2020

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

1 reference

12 December 2020

Antimalarial cyclic peroxy ketals

1 reference

12 December 2020

Fluorescence lifetime characterization of novel low-pH probes

1 reference

12 December 2020

The mitochondrion of Plasmodium falciparum visualized by rhodamine 123 fluorescence

1 reference

12 December 2020

Osmium catalyzed dihydroxylation of 1,2-dioxines: a new entry for stereoselective sugar synthesis

1 reference

12 December 2020

Gentamicin and amikacin repress the growth of Plasmodium falciparum in culture, probably by inhibiting a parasite acid phospholipase

1 reference

12 December 2020

Further evidence supporting the importance of and the restrictions on a carbon-centered radical for high antimalarial activity of 1,2,4-trioxanes like artemisinin

1 reference

12 December 2020

Morphologic effects of artemisinin in Plasmodium falciparum

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.00609-07

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17938190%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references