(Q22241380)

PubMed

PubMed publication ID

17501694

Expert Opinion on Investigational Drugs

7 February 2023

language of work or name

English

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publication date

June 2007

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published in

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volume

16

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issue

6

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page(s)

819-828

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cites work

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A specific amyloid-beta protein assembly in the brain impairs memory

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

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Alzheimer's disease is a synaptic failure

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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The molecular pathology of Alzheimer's disease

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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Alzheimer's disease: a central role for amyloid

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Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau.

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Some morphometric aspects of the brain in senile dementia of the alzheimer type

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Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

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Immunology and immunotherapy of Alzheimer's disease

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

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Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

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Reduction of beta-amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization

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EFRH-phage immunization of Alzheimer's disease animal model improves behavioral performance in Morris water maze trials.

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

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Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

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Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

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A beta immunotherapy: Lessons learned for potential treatment of Alzheimer's disease

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Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease

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Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

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Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with beta-amyloid

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Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease

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Abeta species removal after abeta42 immunization

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Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

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Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

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Mechanisms of action of IVIg and therapeutic considerations in the treatment of acute and chronic demyelinating neuropathies

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Human antibodies against amyloid beta peptide: a potential treatment for Alzheimer's disease.

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Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease

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Intravenous immunoglobulin enhances the clearance of fibrillar amyloid-beta peptide

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Cell mediators of inflammation in the Alzheimer disease brain

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Concern over the amyloid vaccine: amyloid heterogeneity and Fc receptor signaling

21 January 2018

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Open peer commentary regarding Abeta immunization and CNS inflammation by Pasinetti et al.

21 January 2018

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Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

21 January 2018

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Modulation of Alzheimer's beta-amyloid neurotoxicity by site-directed single-chain antibody.

21 January 2018

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Generation of a recombinant Fab antibody reactive with the Alzheimer's disease-related Abeta peptide

21 January 2018

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Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity

21 January 2018

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Filamentous phage as vector-mediated antibody delivery to the brain

21 January 2018

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

21 January 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

21 January 2018

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Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with AD

21 January 2018

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Inhibitory effect of monoclonal antibodies on Alzheimer's β-amyloid peptide aggregation

21 January 2018

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Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

21 January 2018

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7 January 2021

Chaperone-like effect of monoclonal antibodies on refolding of heat-denatured carboxypeptidase A

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7 January 2021

Antibody assisted protein refolding

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7 January 2021

Alzheimer's disease: genes, proteins, and therapy

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7 January 2021

Preventing and treating Alzheimer's disease: strategies and prospects

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7 January 2021