(Q22255611)

English

Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics

scientific article

Ribosomal crystallography: initiation, peptide bond formation, and amino acid polymerization are hampered by antibiotics

In more languages

edit

Statements

0 references

1 reference

Europe PubMed Central

title

Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics (English)

0 references

0 references

1 reference

1

Ada Yonath

Ada

Yonath

1 reference

stated in

PubMed

PubMed publication ID

7 February 2023

2

Anat Bashan

Anat

Bashan

1 reference

stated in

PubMed

PubMed publication ID

15487937

retrieved

7 February 2023

language of work or name

English

0 references

publication date

October 2004

0 references

published in

Annual Review of Microbiology

0 references

volume

58

0 references

issue

1

0 references

page(s)

233-251

0 references

cites work

A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstruction

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Instruction of translating ribosome by nascent peptide

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The crystal structures of chloramphenicol phosphotransferase reveal a novel inactivation mechanism

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosome fidelity: tRNA discrimination, proofreading and induced fit.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Molecular movement inside the translational engine

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Mapping the active sites of bacterial translation initiation factor IF3.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Characterization and preliminary attempts for derivatization of crystals of large ribosomal subunits from Haloarcula marismortui diffracting to 3 A resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Interaction of translation initiation factor 3 with the 30S ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structure of the 30S ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The ribosomal exit tunnel functions as a discriminating gate

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

A Sparsomycin-resistant Mutant ofHalobacterium salinariumLacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The structural basis of ribosome activity in peptide bond synthesis

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Revised translation start site for secM defines an atypical signal peptide that regulates Escherichia coli secA expression

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Initiation of mRNA translation in prokaryotes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes. Delivered on 20 October 2002 at the 28th FEBS Meeting in Istanbul

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Single crystals of large ribosomal particles from Halobacterium marismortui diffract to 6 A

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

THE PUROMYCIN REACTION AND ITS RELATION TO PROTEIN SYNTHESIS

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Erythromycin resistance by ribosome modification

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Arrangement of tRNAs in pre- and posttranslocational ribosomes revealed by electron cryomicroscopy.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Location of translational initiation factor IF3 on the small ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Upstream open reading frames as regulators of mRNA translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The chemistry of protein synthesis and voyage through the ribosomal tunnel

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Base-pairing between 23S rRNA and tRNA in the ribosomal A site

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The 70S Escherichia coli ribosome at 23 A resolution: fitting the ribosomal RNA.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosome structure and the mechanism of translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural insights into peptide bond formation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Controlled proteolysis of nascent polypeptides in rat liver cell fractions. II. Location of the polypeptides in rough microsomes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The structures of four macrolide antibiotics bound to the large ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Eukaryotic initiation factor 3 does not prevent association through physical blockage of the ribosomal subunit-subunit interface

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

tRNA-mediated labelling of proteins with biotin. A nonradioactive method for the detection of cell-free translation products

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The search and its outcome: high-resolution structures of ribosomal particles from mesophilic, thermophilic, and halophilic bacteria at various functional states

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Signal sequence recognition and protein targeting

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Solution structure of the ribosome-binding domain of E. coli translation initiation factor IF3. Homology with the U1A protein of the eukaryotic spliceosome.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Antibiotics targeting ribosomes: crystallographic studies

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosomes and translation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Regulatory nascent peptides in the ribosomal tunnel

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosomal crystallography: peptide bond formation and its inhibition

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Partial resistance of nascent polypeptide chains to proteolytic digestion due to ribosomal shielding

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

After the ribosome structures: how does peptidyl transferase work?

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Throwing a spanner in the works: antibiotics and the translation apparatus

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosomal tolerance and peptide bond formation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Enhanced D-amino acid incorporation into protein by modified ribosomes

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Crystal structure of the ribosome at 5.5 A resolution

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Location of exit channel for nascent protein in 80S ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural Insight Into Functional Aspects of Ribosomal RNA Targeting

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Characterization of crystals of small ribosomal subunits

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural insight into the role of the ribosomal tunnel in cellular regulation

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Intermediate states in the movement of transfer RNA in the ribosome

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The importance of highly conserved nucleotides in the binding region of chloramphenicol at the peptidyl transfer centre of Escherichia coli 23S ribosomal RNA.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structural basis for the antibiotic activity of ketolides and azalides

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Chloramphenicol acetyltransferase

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Macrolide resistance conferred by base substitutions in 23S rRNA.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Chloramphenicol resistance mutations in the single 23S rRNA gene of the archaeon Halobacterium halobium

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1146/ANNUREV.MICRO.58.030603.123822

Identifiers

DOI

10.1146/ANNUREV.MICRO.58.030603.123822

0 references

Fatcat ID

release_zfi6wekow5dlba7c5qgxyqkmym

1 reference

stated in

Fatcat

reference URL

https://api.fatcat.wiki/v0/release/zfi6wekow5dlba7c5qgxyqkmym

retrieved

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

15487937

0 references

ResearchGate publication ID

8228759

0 references

(Q22255611)

Ribosomal Crystallography: Initiation, Peptide Bond Formation, and Amino Acid Polymerization are Hampered by Antibiotics

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)