Wikidata

(Q22676777)

English

ERCC excision repair 4, endonuclease catalytic subunit

mammalian protein found in Homo sapiens

  • DNA repair endonuclease XPF
  • excision-repair, complementing defective, in Chinese hamster
  • excision repair cross-complementation group 4
  • DNA excision repair protein ERCC-4
  • DNA repair protein complementing XP-F cells
  • ERCC4
  • xeroderma pigmentosum, complementation group F
  • excision repair cross-complementing rodent repair deficiency, complementation group 4
  • xeroderma pigmentosum, complementation group F protein
  • xeroderma pigmentosum group F-complementing protein
In more languages

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Nonerythroid alphaII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases
GOA
curator
UniProt
UniProt protein ID
Q92889
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
Human XPF controls TRF2 and telomere length maintenance through distinctive mechanisms
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
retrieved
8 April 2019
stated in
SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92889
determination method
IPI
cell component
biological process

Identifiers

 
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