(Q23911011)

English

An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat

journal article published in 2007

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scholarly article

1 reference

19 July 2017

An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat (English)

1 reference

12 July 2017

National Institute for Occupational Safety and Health

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2 references

19 July 2017

29 March 2020

1 reference

19 July 2017

exposure assessment

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19 July 2017

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1 reference

29 March 2020

1 reference

29 March 2020

pharmacodynamics

1 reference

based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

inferred from title

author name string

C. Timchalk

1

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A. A. Kousba

2

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T. S. Poet

3

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language of work or name

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publication date

10 April 2007

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Toxicological Sciences

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98

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2

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348-365

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performing organization

Battelle Memorial Institute

object named as

Battelle Memorial Institute, Richland, Washington

1 reference

2 February 2024

on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

0 references

1 reference

25 September 2023

Maturational differences in chlorpyrifos-oxonase activity may contribute to age-related sensitivity to chlorpyrifos.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Tissue-specific effects of chlorpyrifos on carboxylesterase and cholinesterase activity in adult rats: an in vitro and in vivo comparison.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic polymorphisms in human drug metabolic enzymes

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Computer simulation of the lactational transfer of tetrachloroethylene in rats using a physiologically based model

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related differences in parathion and chlorpyrifos toxicity in male rats: target and nontarget esterase sensitivity and cytochrome P450-mediated metabolism.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age- and gender-related differences in the time course of behavioral and biochemical effects produced by oral chlorpyrifos in rats.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetics of methylmercury and inorganic mercury in lactating and nonlactating mice

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related changes in acetylcholinesterase and its molecular forms in various brain areas of rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Size and charge isomers of acetylcholinesterase in the cerebral cortex of young and aged rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

AGE VARIATION IN PLASMA ARYLESTERASE ACTIVITY IN CHILDREN

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

The influence of age on the toxicity and metabolism of methyl parathion and parathion in male and female rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative toxicity of some selected pesticides in neonatal and adult rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Chlorpyrifos: Pharmacokinetics in human volunteers

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of blood flow and detoxification on in vivo cholinesterase inhibition by soman in rats

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiologically based pharmacokinetic modeling of the lactating rat and nursing pup: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiologically based pharmacokinetic and pharmacodynamic model for the inhibition of acetylcholinesterase by diisopropylfluorophosphate

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related effects of chlorpyrifos on acetylcholine release in rat brain

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetic parameters of desulfuration and dearylation of parathion and chlorpyrifos by rat liver microsomes

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Rat brain acetylcholinesterase activity: developmental profile and maturational sensitivity to carbamate and organophosphorus inhibitors.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related differences in sensitivity to organophosphorus pesticides.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Organ weights and fat volume in rats as a function of strain and age.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Physicochemical and biological data for the development of predictive organophosphorus pesticide QSARs and PBPK/PD models for human risk assessment

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Children's susceptibility to chemicals: a review by developmental stage

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Physiological modeling of age-specific changes in the pharmacokinetics of organic chemicals in children

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian toxicology of organophosphorus pesticides.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Review and evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of Physiologically Based Models of Pregnancy and Lactation for Their Application in Children's Health Risk Assessments

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Changes in rat brain cholinesterase activity and muscarinic receptor density during and after repeated oral exposure to chlorpyrifos in early postnatal development.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of repeated oral postnatal exposure to chlorpyrifos on open-field behavior in juvenile rats.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Predicting neonatal perchlorate dose and inhibition of iodide uptake in the rat during lactation using physiologically-based pharmacokinetic modeling

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of chlorpyrifos-oxon and paraoxon acetylcholinesterase inhibition dynamics: potential role of a peripheral binding site

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Paraoxonase (PON1) gene in mice: sequencing, chromosomal localization and developmental expression.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

The cholinesterases: from genes to proteins

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Ontogeny of hepatic and renal systemic clearance pathways in infants: part II.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

COMPARISON OF ACUTE TOXICITY OF ANTICHOLINESTERASE INSECTICIDES TO WEANLING AND ADULT MALE RATS

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFM119

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1093/TOXSCI/KFM119

0 references

release_vedos2wkqfeclocht4jnzlfhfa

1 reference

https://api.fatcat.wiki/v0/release/vedos2wkqfeclocht4jnzlfhfa

24 November 2022

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mapped directly with Wikidata item

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PubMed publication ID

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