(Q24290586)

English

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

GOA release 2020-03-11

glycogen synthase kinase 3 beta

1 reference

GOA release 2020-03-11

peptidyl-serine phosphorylation

1 reference

GOA release 2020-03-11

Catenin (cadherin associated protein), beta 1

1 reference

GOA release 2020-03-11

phosphorylation

1 reference

based on heuristic

inferred from title

Justin V McCarthy

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Kirschenbaum F

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Hsu SC

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Cordell B

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

0 references

publication date

4 December 2000

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

number of pages

10

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

276

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

7366-7375

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Presenilin mutations in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

The role of presenilins in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Direct association of presenilin-1 with beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced abeta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

21 January 2018

Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004697200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M004697200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104755%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24290586&oldid=1769169104"