(Q24292187)

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Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6

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Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6 (English)

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1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

MutY DNA glycosylase

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GOA release 2020-03-11

MutSbeta complex binding

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GOA release 2020-03-11

DNA mismatch repair

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based on heuristic

inferred from title

author name string

Yesong Gu

1

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Antony Parker

2

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Teresa M Wilson

3

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Haibo Bai

4

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Dau-Yin Chang

5

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A-Lien Lu

6

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language of work or name

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publication date

29 March 2002

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Journal of Biological Chemistry

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277

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13

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11135-42

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PCNA binding through a conserved motif

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https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Repair of DNA containing the oxidatively-damaged base, 8-oxoguanine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mismatch repair and cancer susceptibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mismatch repair deficient human cells: spontaneous and MNNG-induced mutational spectra in the HPRT gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for PCNA in DNA mismatch repair at a step preceding DNA resynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

8-hydroxyguanine (7,8-dihydro-8-oxoguanine) DNA glycosylase and AP lyase activities of hOGG1 protein and their substrate specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

MutS homologs in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Eukaryotic DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G mispairs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mismatch repair defects and O6-methylguanine-DNA methyltransferase expression in acquired resistance to methylating agents in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the recombinant MutY homolog, an adenine DNA glycosylase, from yeast Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Dissociation of mismatch recognition and ATPase activity by hMSH2-hMSH3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional interaction of proliferating cell nuclear antigen with MSH2-MSH6 and MSH2-MSH3 complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Steady-state regulation of the human DNA mismatch repair system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a physical interaction between the Escherichia coli methyl-directed mismatch repair proteins MutL and UvrD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential subcellular localization of human MutY homolog (hMYH) and the functional activity of adenine:8-oxoguanine DNA glycosylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Purification and characterization of a mammalian homolog of Escherichia coli MutY mismatch repair protein from calf liver mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential DNA recognition and glycosylase activity of the native human MutY homolog (hMYH) and recombinant hMYH expressed in bacteria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

hMYH cell cycle-dependent expression, subcellular localization and association with replication foci: evidence suggesting replication-coupled repair of adenine:8-oxoguanine mispairs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemistry and genetics of eukaryotic mismatch repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations of GTBP in genetically unstable cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA repair in eukaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

Repair of A/G and A/8-oxoG mismatches by MutY adenine DNA glycosylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108618200

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1074/JBC.M108618200

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