(Q24293342)

GOA release 2020-03-11

heme binding

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

3

Irina A Pikuleva

0 references

author name string

Natalia Mast

series ordinal

1

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Casey Charvet

series ordinal

2

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C David Stout

series ordinal

4

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language of work or name

English

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publication date

8 October 2010

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published in

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volume

285

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issue

41

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page(s)

31783-95

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cites work

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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

19 March 2017

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Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

19 March 2017

1 reference

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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

19 March 2017

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Interaction of Mycobacterium tuberculosis CYP130 with Heterocyclic Arylamines

19 March 2017

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Structural and Thermodynamic Consequences of 1-(4-Chlorophenyl)imidazole Binding to Cytochrome P450 2B4 † , ‡

19 March 2017

1 reference

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Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam

19 March 2017

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Phasercrystallographic software

19 March 2017

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Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

19 March 2017

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Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

19 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

19 March 2017

1 reference

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Detection, delineation, measurement and display of cavities in macromolecular structures

19 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

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Integration of macromolecular diffraction data

19 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

19 March 2017

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Cytochrome P450s and cholesterol homeostasis

19 March 2017

1 reference

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Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain

19 March 2017

1 reference

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Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

19 March 2017

1 reference

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Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

19 March 2017

1 reference

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Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

19 March 2017

1 reference

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Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease

19 March 2017

1 reference

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The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo

27 September 2017

1 reference

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Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan

27 September 2017

1 reference

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New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

27 September 2017

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Tranylcypromine: new perspectives on an "old" drug

27 September 2017

1 reference

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Brain cholesterol turnover required for geranylgeraniol production and learning in mice

27 September 2017

1 reference

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Functional interaction of nitrogenous organic bases with cytochrome P450: a critical assessment and update of substrate features and predicted key active-site elements steering the access, binding, and orientation of amines

27 September 2017

1 reference

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Keynote review: histamine H3 receptor antagonists reach out for the clinic

27 September 2017

1 reference

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Voriconazole: a new triazole antifungal

27 September 2017

1 reference

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On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

27 September 2017

1 reference

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Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.143313

How do azoles inhibit cytochrome P450 enzymes? A density functional study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.143313

Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization.

21 January 2018

1 reference

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Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.143313

Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.143313

Spectroscopic investigations of ferric cytochrome P-450-CAM ligand complexes. Identification of the ligand trans to cysteinate in the native enzyme

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20667828