(Q24293500)

GOA release 2020-03-11

author

Alfred Wittinghofer

9

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Herbert Waldmann

11

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Gemma Triola

8

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Stephan Hahn

object named as

Stephan A Hahn

7

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Shehab A Ismail

object named as

Shehab Ismail

3

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author name string

Gunther Zimmermann

1

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Björn Papke

2

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Nachiket Vartak

4

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Anchal Chandra

5

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Maike Hoffmann

6

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Philippe I H Bastiaens

RAS oncogenes: the first 30 years.

10

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language of work or name

English

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publication date

30 May 2013

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published in

Nature

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volume

497

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issue

7451

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page(s)

638-42

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Therapeutic intervention based on protein prenylation and associated modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Targeting protein prenylation for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

An orthosteric inhibitor of the Ras-Sos interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Photoreceptor cGMP Phosphodiesterase δ Subunit (PDEδ) Functions as a Prenyl-binding Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Synthesis of the Rheb and K-Ras4B GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

UNC119 is required for G protein trafficking in sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Galectin-1 binds oncogenic H-Ras to mediate Ras membrane anchorage and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Imaging biochemistry inside cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Global analysis of time correlated single photon counting FRET-FLIM data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12205

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23698361