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The association of Sam68 with Vav1 contributes to tumorigenesis
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scholarly article
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title
The association of Sam68 with Vav1 contributes to tumorigenesis
(English)
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author name string
Galit Lazer
series ordinal
1
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Liron Pe'er
series ordinal
2
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Vered Schapira
series ordinal
3
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Stéphane Richard
series ordinal
4
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Shulamit Katzav
series ordinal
5
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language of work or name
English
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publication date
December 2007
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published in
Cellular Signalling
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volume
19
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page(s)
2479-86
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issue
12
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cites work
The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas
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The mechanism of action of cyclosporin A and FK506.
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KH domain integrity is required for wild-type localization of Sam68.
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A new technique for the assay of infectivity of human adenovirus 5 DNA
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Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies
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Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Vav-family proteins in T-cell signalling
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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The Actin Cytoskeleton and Lymphocyte Activation
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Vav proteins, masters of the world of cytoskeleton organization.
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Proximal protein tyrosine kinases in immunoreceptor signaling
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Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
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BLNK: a central linker protein in B cell activation
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The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation
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Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Analytical properties of the nanoelectrospray ion source
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7 January 2021
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An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
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Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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VAV proteins as signal integrators for multi-subunit immune-recognition receptors
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Mutagenic analysis of Vav reveals that an intact SH3 domain is required for transformation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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p95(vav) associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-alpha in megakaryocytic cell lines
1 reference
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reference URL
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Characterization of VIK-1: a new Vav-interacting Kruppel-like protein
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Binding of Vav to Grb2 through dimerization of Src homology 3 domains
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Functional interaction between c-Src and its mitotic target, Sam 68
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line
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7 January 2021
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P62 association with RNA is regulated by tyrosine phosphorylation.
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Specificity and determinants of Sam68 RNA binding. Implications for the biological function of K homology domains
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7 January 2021
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Vav binding to heterogeneous nuclear ribonucleoprotein (hnRNP) C. Evidence for Vav-hnRNP interactions in an RNA-dependent manner.
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Neoplastic transformation and tumorigenesis associated with sam68 protein deficiency in cultured murine fibroblasts
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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inferred from DOI database lookup
Vav1 and Ly-GDI two regulators of Rho GTPases, function cooperatively as signal transducers in T cell antigen receptor-induced pathways
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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inferred from DOI database lookup
Structural determinants for the biological activity of Vav proteins.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression
1 reference
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inferred from DOI database lookup
Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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inferred from DOI database lookup
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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inferred from DOI database lookup
Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.
1 reference
stated in
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav1 is a component of transcriptionally active complexes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nuclear RNA-binding protein Sam68 translocates to the cytoplasm and associates with the polysomes in mouse spermatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the VAV proto-oncogene product is associated with B-cell chronic lymphocytic leukaemia displaying loss on 13q.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
based on heuristic
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Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
based on heuristic
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A functional T-cell receptor signaling pathway is required for p95vav activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
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p95vav associates with the nuclear protein Ku-70
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
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Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory and signaling properties of the Vav family
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoter
1 reference
stated in
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav1: an oncogene that regulates specific transcriptional activation of T cells
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Depolarization-induced translocation of the RNA-binding protein Sam68 to the dendrites of hippocampal neurons.
1 reference
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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
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7 January 2021
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Specific subdomains of Vav differentially affect T cell and NK cell activation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2007.07.022
retrieved
7 January 2021
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Identifiers
DOI
10.1016/J.CELLSIG.2007.07.022
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PubMed ID
17855053
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