(Q24293674)

4

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author name string

Shiqing Li

1

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Rafael S Depetris

2

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David Barford

Shape complementarity at protein/protein interfaces

3

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language of work or name

English

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publication date

November 2005

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published in

Structure

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volume

13

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page(s)

1643-51

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issue

11

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cites work

1 reference

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7 January 2021

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

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Interaction of PTPB with the insulin receptor precursor during its biosynthesis in the endoplasmic reticulum

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7 January 2021

PTP1B: from the sidelines to the front lines!

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The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells

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Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

From form to function: signaling by protein tyrosine phosphatases.

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Insulin signaling pathways in time and space.

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Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B

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PTP1B regulates leptin signal transduction in vivo

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7 January 2021

The IRS-signalling system: a network of docking proteins that mediate insulin action

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Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

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Allosteric inhibition of protein tyrosine phosphatase 1B.

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Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells

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7 January 2021

APS, an adapter protein with a PH and SH2 domain, is a substrate for the insulin receptor kinase

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7 January 2021

Interaction of protein tyrosine phosphatase (PTP) 1B with its substrates is influenced by two distinct binding domains

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SH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinase

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Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

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Direct binding of the proline-rich region of protein tyrosine phosphatase 1B to the Src homology 3 domain of p130(Cas)

1 reference

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7 January 2021

Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

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7 January 2021

Identification of the APS protein as a novel insulin receptor substrate

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7 January 2021

Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1

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7 January 2021

Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation

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TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

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Down-regulation of Insulin Signaling by Protein-tyrosine Phosphatase 1B Is Mediated by an N-terminal Binding Region

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7 January 2021

Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor

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7 January 2021

Protein tyrosine phosphatase-1B dephosphorylation of the insulin receptor occurs in a perinuclear endosome compartment in human embryonic kidney 293 cells

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7 January 2021

Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B.

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7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

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7 January 2021

Protein-tyrosine phosphatase 1B associates with insulin receptor and negatively regulates insulin signaling without receptor internalization

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

AMoRe: an automated package for molecular replacement

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

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7 January 2021

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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7 January 2021

Crystal structure of human protein tyrosine phosphatase 1B

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7 January 2021

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

1 reference

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7 January 2021

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

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7 January 2021

Structural and evolutionary relationships among protein tyrosine phosphatase domains

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7 January 2021

Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP

1 reference

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7 January 2021

Protein tyrosine phosphatases: the quest for negative regulators of insulin action

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7 January 2021