(Q24296243)

GOA release 2020-03-11

Insulin degrading enzyme

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GOA release 2020-03-11

protease binding

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Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese.

GOA release 2020-03-11

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Wei-Jie Zhang

1

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Xiao Luo

series ordinal

2

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Zhan-Yun Guo

series ordinal

3

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language of work or name

English

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publication date

February 2010

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published in

The Protein Journal

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volume

29

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issue

2

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page(s)

93-8

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cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10930-009-9226-8

Insulin-degrading enzyme is exported via an unconventional protein secretion pathway

21 January 2018

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12 December 2020

Cryptorchidism in mice mutant for Insl3

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12 December 2020

Degradation of amylin by insulin-degrading enzyme

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12 December 2020

Functional human insulin-degrading enzyme can be expressed in bacteria

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12 December 2020

Degradation of insulin-like growth factors I and II by a human insulin degrading enzyme

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12 December 2020

The role of insulinase in the regulation of carbohydrate metabolism

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12 December 2020

Degradation of relaxin family peptides by insulin-degrading enzyme

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12 December 2020

The rat insulin-degrading enzyme. Molecular cloning and characterization of tissue-specific transcripts

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12 December 2020

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

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12 December 2020

Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues

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12 December 2020

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

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12 December 2020

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.

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12 December 2020

Dynamics of INSL3 peptide expression in the rodent testis

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12 December 2020

The inactivation of insulin by tissue extracts; the effect of fasting on the insulinase content of rat liver.

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12 December 2020

Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population

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12 December 2020

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

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12 December 2020

An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures

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12 December 2020

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

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12 December 2020

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

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12 December 2020

Identification of gamma-endorphin-generating enzyme as insulin-degrading enzyme

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12 December 2020

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

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12 December 2020

Paracrine regulation of mammalian oocyte maturation and male germ cell survival

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12 December 2020

The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G protein-activated receptor 8.

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12 December 2020

Molecular Basis of Catalytic Chamber-assisted Unfolding and Cleavage of Human Insulin by Human Insulin-degrading Enzyme

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12 December 2020

Recombinant expression of an insulin-like peptide 3 (INSL3) precursor and its enzymatic conversion to mature human INSL3.

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12 December 2020

The human insulin superfamily of polypeptide hormones

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12 December 2020

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease

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12 December 2020

Atrial natriuretic peptide (ANP) is a high-affinity substrate for rat insulin-degrading enzyme

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12 December 2020

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels

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12 December 2020

Identification of the cleavage sites of transforming growth factor alpha by insulin-degrading enzymes

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12 December 2020

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

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12 December 2020

INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

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12 December 2020

Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme †

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12 December 2020

GREAT/LGR8 is the only receptor for insulin-like 3 peptide

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12 December 2020

Structure, function, and regulation of insulin-degrading enzyme

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12 December 2020

Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry

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12 December 2020

Proteolytic fragments of insulysin (IDE) retain substrate binding but lose allosteric regulation

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12 December 2020

Cellular distribution of insulin-degrading enzyme gene expression. Comparison with insulin and insulin-like growth factor receptors

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12 December 2020

Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin

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12 December 2020

Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity

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12 December 2020