(Q24297510)

Phosphofructokinase, liver type

GOA release 2020-03-11

1 reference

fructose 1,6-bisphosphate metabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Wen Yi

1

0 references

Peter M Clark

2

0 references

Daniel E Mason

3

0 references

Marie C Keenan

4

0 references

Collin Hill

5

0 references

William A Goddard

6

0 references

Eric C Peters

7

0 references

Edward M Driggers

8

0 references

Linda C Hsieh-Wilson

Regulation of cellular metabolism by protein lysine acetylation

9

0 references

language of work or name

English

0 references

publication date

24 August 2012

0 references

published in

Science

0 references

volume

337

0 references

page(s)

975-80

0 references

issue

6097

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Understanding the Warburg effect: the metabolic requirements of cell proliferation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Triose phosphate isomerase deficiency is caused by altered dimerization--not catalytic inactivity--of the mutant enzymes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Pyruvate kinase M2 is a phosphotyrosine-binding protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Regulation of cancer cell metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Cancer cell metabolism: Warburg and beyond

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity

19 March 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1222278

Growth factors can influence cell growth and survival through effects on glucose metabolism

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1222278

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

7 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Ras, PI(3)K and mTOR signalling controls tumour cell growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Targeting metabolic transformation for cancer therapy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The molecular determinants of de novo nucleotide biosynthesis in cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Chemical approaches to understanding O-GlcNAc glycosylation in the brain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Direct in-gel fluorescence detection and cellular imaging of O-GlcNAc-modified proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection-time-of-flight mass spectrometry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Subunit interactions and composition of the fructose 6-phosphate catalytic site and the fructose 2,6-bisphosphate allosteric site of mammalian phosphofructokinase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Hepatic glucose sensing via the CREB coactivator CRTC2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

The interplay between MYC and HIF in cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3534962

Cellular ATP depletion by LY309887 as a predictor of growth inhibition in human tumor cell lines

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22923583

12 December 2020

inferred from PubMed ID database lookup

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Ultrahigh performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Comparison of metabolic flux distributions for MDCK cell growth in glutamine- and pyruvate-containing media.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Flat-Bottom Strategy for Improved Accuracy in Protein Side-Chain Placements

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

O-GlcNAc signalling: implications for cancer cell biology

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Phosphorylation of Bad at Thr-201 by JNK1 promotes glycolysis through activation of phosphofructokinase-1.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Quiescent fibroblasts exhibit high metabolic activity.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1222278

7 January 2021

Identifiers

DOI

10.1126/SCIENCE.1222278

1 reference

1286920

1286920

1 reference

1 reference

1 reference