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CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha
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title
CSN controls NF-kappaB by deubiquitinylation of IkappaBalpha
(English)
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main subject
NF-κB
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author
Wolfgang Dubiel
object named as
Wolfgang Dubiel
series ordinal
3
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author name string
Katrin Schweitzer
series ordinal
1
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Przemyslaw M Bozko
series ordinal
2
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Michael Naumann
series ordinal
4
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language of work or name
English
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publication date
21 March 2007
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published in
The EMBO Journal
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volume
26
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issue
6
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page(s)
1532-41
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cites work
Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels
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The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1
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Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases
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The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage
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CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex
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19 March 2017
NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases
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The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p
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COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
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A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
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The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B
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19 March 2017
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway
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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
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19 March 2017
Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.
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Function and regulation of cullin-RING ubiquitin ligases
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19 March 2017
The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases?
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19 March 2017
COP9 signalosome revisited: a novel mediator of protein degradation
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19 March 2017
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
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19 March 2017
COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK
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Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1
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The COP9 signalosome regulates Skp2 levels and proliferation of human cells.
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27 September 2017
The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex
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27 September 2017
Nedd8 on cullin: building an expressway to protein destruction.
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PubMed Central
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27 September 2017
COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases
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27 September 2017
COP9 signalosome: a provider of DNA building blocks
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PubMed Central
reference URL
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27 September 2017
Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms
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PubMed Central
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27 September 2017
The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis.
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PubMed Central
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27 September 2017
Cytokine-induced stabilization of newly synthesized I(kappa)B-alpha
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PubMed Central
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27 September 2017
Activation of NF-kappa B in vivo is regulated by multiple phosphorylations
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
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27 September 2017
Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
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29 November 2018
CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
retrieved
29 November 2018
Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
retrieved
29 November 2018
Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
retrieved
29 November 2018
Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829370
retrieved
29 November 2018
Identifiers
DOI
10.1038/SJ.EMBOJ.7601600
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1153074
OpenCitations bibliographic resource ID
1153074
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1153074
PMC publication ID
1829370
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1153074
PubMed publication ID
17318178
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1153074
ResearchGate publication ID
6488363
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