(Q24298961)

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Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway

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Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway (English)

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Chitinase domain containing 1

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GOA release 2020-03-11

Elisabeth Kremmer

4

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Alexei Gratchev

object named as

Alexei Gratchev

3

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Jochen Utikal

8

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Srinivas Mamidi

2

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Srinivas Mamidi

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author name string

Julia Kzhyshkowska

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Christina Schmuttermaier

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Liis Krusell

6

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Georg Haus

7

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Kai Schledzewski

9

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Joachim Scholtze

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Sergij Goerdt

11

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language of work or name

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publication date

15 April 2006

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107

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3221-8

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Cellular expression of murine Ym1 and Ym2, chitinase family proteins, as revealed by in situ hybridization and immunohistochemistry

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Phosphatidylinositide 3-kinase activity is required for stabilin-1-mediated endosomal transport of acLDL.

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Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage

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Regulated secretion of conventional lysosomes

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Other functions, other genes: alternative activation of antigen-presenting cells

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Alternative activation of macrophages

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Mannose 6-phosphate receptors: new twists in the tale

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The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways

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The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha

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Lysosomal and cytosolic pH as regulators of exocytosis in mouse macrophages

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10.1182/BLOOD-2005-07-2843

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