(Q24299061)

3

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Christopher J. Schofield

5

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Peter J. Ratcliffe

Peter J Ratcliffe

8

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David Ian Stuart

David I Stuart

9

0 references

Timothy D W Claridge

4

Timothy D W Claridge

0 references

Christopher J A Pugh

6

Christopher W Pugh

0 references

Yvonne Jones

10

E Yvonne Jones

0 references

Patrick H. Maxwell

7

Patrick H Maxwell

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author name string

Wai-Ching Hon

1

0 references

Michael I Wilson

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

2

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language of work or name

English

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publication date

27 June 2002

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published in

Nature

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volume

417

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page(s)

975-8

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issue

6892

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cites work

1 reference

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

20 April 2017

1 reference

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

20 April 2017

1 reference

20 April 2017

1 reference

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

20 April 2017

1 reference

A conserved family of prolyl-4-hydroxylases that modify HIF

20 April 2017

1 reference

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

20 April 2017

1 reference

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

20 April 2017

1 reference

Shape complementarity at protein/protein interfaces

20 April 2017

1 reference

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

20 April 2017

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

20 April 2017

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 April 2017

1 reference

Use of non-crystallographic symmetry in protein structure refinement

20 April 2017

1 reference

The CCP4 suite: programs for protein crystallography

20 April 2017

1 reference

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Proteolysis and the cell cycle: with this RING I do thee destroy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Software and database for the analysis of mutations in the VHL gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Hydrogen bonding and biological specificity analysed by protein engineering

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Rapid automated molecular replacement by evolutionary search

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE00767

7 January 2021

Identifiers

DOI

10.1038/NATURE00767

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1425010

1001509797

0 references

1425010

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference