(Q24299990)

GOA release 2020-03-11

drug binding

1 reference

GOA release 2020-03-11

author name string

Chao-Xin Hu

1

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Zhi-Li Zuo

2

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Bing Xiong

3

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Jin-Gui Ma

4

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Mei-Yu Geng

5

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Li-Ping Lin

6

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Hua-Liang Jiang

7

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Jian Ding

Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells

8

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language of work or name

English

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publication date

November 2006

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published in

Molecular Pharmacology

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volume

70

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issue

5

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page(s)

1593-601

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cites work

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Eukaryotic DNA topoisomerase II beta

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

A quantitative decatenation assay for type II topoisomerases

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Induction of bulk and c-myc P2 promoter-specific DNA damage by an anti-topoisomerase II agent salvicine is an early event leading to apoptosis in HL-60 cells

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Catalytic topoisomerase II inhibitors in cancer therapy.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Synthesis and antitumour activity of novel diterpenequinone salvicine and the analogs

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Analysis of etoposide binding to subdomains of human DNA topoisomerase II alpha in the absence of DNA.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Structure-based virtual screening: an application to human topoisomerase II alpha.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Structure and mechanism of DNA topoisomerase II

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Cellular roles of dna topoisomerases: a molecular perspective

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Kinetic and thermodynamic analysis of mutant type II DNA topoisomerases that cannot covalently cleave DNA.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Atp-bound topoisomerase ii as a target for antitumor drugs

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Topoisomerase II poisoning by ICRF-193.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

ATPase domain of eukaryotic DNA topoisomerase II. Inhibition of ATPase activity by the anti-cancer drug bisdioxopiperazine and ATP/ADP-induced dimerization

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

A two-drug model for etoposide action against human topoisomerase IIalpha

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase.

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Use of a rapid throughput in vivo screen to investigate inhibitors of eukaryotic topoisomerase II enzymes

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Antimetastatic effect of salvicine on human breast cancer MDA-MB-435 orthotopic xenograft is closely related to Rho-dependent pathway

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

The ATP-binding site of type II topoisomerases as a target for antibacterial drugs

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Stabilization of eukaryotic topoisomerase II-DNA cleavage complexes

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Neuronal nicotinic acetylcholine receptor agonists: pharmacophores, evolutionary QSAR and 3D-QSAR models

1 reference

https://api.crossref.org/works/10.1124%2FMOL.106.027714

7 January 2021

Identifiers

DOI

10.1124/MOL.106.027714

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16914642

1 reference

Consolidated OpenCitations Corpus – April 2017