(Q24300290)

double-strand break repair

GOA release 2020-03-11

1 reference

Breast cancer 1, early onset

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

myocardial infarction

1 reference

15

Howard Leong-Poi

0 references

Toren Finkel

19

object named as

Toren Finkel

0 references

Ilsa I Rovira

8

object named as

Ilsa I Rovira

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author name string

Praphulla C Shukla

1

0 references

Krishna K Singh

2

0 references

Adrian Quan

3

0 references

Mohammed Al-Omran

4

0 references

Hwee Teoh

5

0 references

Fina Lovren

6

0 references

Liu Cao

7

0 references

Yi Pan

9

0 references

Christine Brezden-Masley

10

0 references

Bobby Yanagawa

11

0 references

Aanika Gupta

12

0 references

Chu-Xia Deng

13

0 references

John G Coles

14

0 references

William L Stanford

16

0 references

Thomas G Parker

17

0 references

Michael D Schneider

18

0 references

Subodh Verma

Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

20

0 references

language of work or name

English

0 references

publication date

2011

0 references

published in

Nature Communications

0 references

volume

2

0 references

page(s)

593

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copyright license

start time

1 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3247816/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The DNA-damage response in human biology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Inducible gene targeting in mice using the Cre/lox system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Cancer-susceptibility genes. Gatekeepers and caretakers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

In search of the tumour-suppressor functions of BRCA1 and BRCA2

19 March 2017

1 reference

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19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Potential excess mortality in BRCA1/2 mutation carriers beyond breast, ovarian, prostate, and pancreatic cancers, and melanoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Inherited susceptibility to common cancers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Narrative review: cardiopulmonary resuscitation and emergency cardiovascular care: review of the current guidelines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Cardioprotective stress response in the human fetal heart

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

The role of BRCA1 in the cellular response to chemotherapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Breast and ovarian cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Telomere attrition and Chk2 activation in human heart failure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Homologous repair of DNA damage and tumorigenesis: the BRCA connection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Developmental studies of Brca1 and Brca2 knock-out mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

The BRCA1 and BRCA2 breast cancer genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Transient global ischemia triggers expression of the DNA damage-inducible gene GADD45 in the rat brain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Phosphorylation and translocation of heat shock protein 27 and alphaB-crystallin in human myocardium after cardioplegia and cardiopulmonary bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

The relationship between BcI2, Bax and p53: consequences for cell cycle progression and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1601

Inhibition of p53 after acute myocardial infarction: reduction of apoptosis is counteracted by disturbed scar formation and cardiac rupture

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247816

Apoptosis in the failing human heart

29 November 2018

1 reference

12 December 2020

Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart

1 reference

12 December 2020

Apoptosis in human acute myocardial infarction

1 reference

12 December 2020

S100B expression modulates left ventricular remodeling after myocardial infarction in mice

1 reference

12 December 2020

Targeted deletion of p53 prevents cardiac rupture after myocardial infarction in mice

1 reference

12 December 2020

The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin

1 reference

12 December 2020

Evidence for DNA damage in patients with coronary artery disease

1 reference

12 December 2020

Testing for doxorubicin cardiotoxicity

1 reference

12 December 2020

Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction

1 reference

12 December 2020

Apoptosis in ischemic and reperfused rat myocardium

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS1601

1 reference

Dimensions Publication ID

ADS bibcode

2011NatCo...2..593S

0 references

1001535134

0 references

1 reference

1 reference

PubMed publication ID

22186889

1 reference