(Q24300314)

English

Solution Structure of the C-terminal Domain of the Ciliary Neurotrophic Factor (CNTF) Receptor and Ligand Free Associations among Components of the CNTF Receptor Complex

scientific article published on April 21, 2003

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scholarly article

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Solution structure of the C-terminal domain of the ciliary neurotrophic factor (CNTF) receptor and ligand free associations among components of the CNTF receptor complex (English)

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Solution Structure of the C-terminal Domain of the Ciliary Neurotrophic Factor (CNTF) Receptor and Ligand Free Associations among Components of the CNTF Receptor Complex (English)

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

ciliary neurotrophic factor receptor complex

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

Ciliary neurotrophic factor receptor

1 reference

GOA release 2020-03-11

Interleukin 6 signal transducer

1 reference

GOA release 2020-03-11

LIF receptor subunit alpha

1 reference

GOA release 2020-03-11

ciliary neurotrophic factor receptor binding

1 reference

GOA release 2020-03-11

solution structure

1 reference

based on heuristic

inferred from title

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

7

object named as

Nancy Y. Ip

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707266

26 December 2023

author name string

David Man

1

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Wei He

2

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Kong Hung Sze

3

0 references

Ke Gong

4

0 references

Guang Zhu

6

0 references

David K. Smith

5

0000-0003-3608-0586

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707266

26 December 2023

language of work or name

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publication date

27 June 2003

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21 April 2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707266

26 December 2023

full work available at URL

http://www.jbc.org/article/S0021925820861250/pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12707266

26 December 2023

https://api.elsevier.com/content/article/PII:S0021925820861250?httpAccept=text/xml

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

https://api.elsevier.com/content/article/PII:S0021925820861250?httpAccept=text/plain

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

https://syndication.highwire.org/content/doi/10.1074/jbc.M301976200

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

Journal of Biological Chemistry

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278

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23285-94

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26

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Gp130 and the interleukin-6 family of cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

The ciliary neurotrophic factor and its receptor, CNTFR alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Janus kinases: components of multiple signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Crystal structure of a cytokine-binding region of gp130.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Structure of an extracellular gp130 cytokine receptor signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Complete 1H, 15N and 13C assignments of the carboxyl terminal domain of the ciliary neurotrophic factor receptor (CNTFR).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

In vitro binding of ciliary neurotrophic factor to its receptors: evidence for the formation of an IL-6-type hexameric complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Interleukin-6: structure-function relationships.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

The immunoglobulin-like module of gp130 is required for signaling by interleukin-6, but not by leukemia inhibitory factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Membrane distal cytokine binding domain of LIFR interacts with soluble CNTFR in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Recombinant human CNTF receptor alpha: production, binding stoichiometry, and characterization of its activity as a diffusible factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from beta-spectrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

A J-multiplied HMQC (MJ-HMQC) experiment for measuring (3)J(HNHalpha) coupling constants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

The interactions of the cytokine-binding homology region and immunoglobulin-like domains of gp130 with oncostatin M: implications for receptor complex formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor alpha mutated in the predicted gp130-binding interface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Deviations from the simple two-parameter model-free approach to the interpretation of nitrogen-15 nuclear magnetic relaxation of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Localization of functional receptor epitopes on the structure of ciliary neurotrophic factor indicates a conserved, function-related epitope topography among helical cytokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

An automated approach for clustering an ensemble of NMR-derived protein structures into conformationally related subfamilies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

21 January 2018

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301976200

7 January 2021

based on heuristic

inferred from DOI database lookup

The Amyotrophic Lateral Sclerosis Functional Rating Scale

5

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region

12

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity

30

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

Quantitative J correlation: a new approach for measuring homonuclear three-bond J(HNH.alpha.) coupling constants in 15N-enriched proteins

36

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

LIF receptor-gp130 interaction investigated by homology modeling: implications for LIF binding

45

1 reference

10.1074/JBC.M301976200

https://api.crossref.org/works/10.1074/JBC.M301976200

26 December 2023

Identifiers

10.1074/JBC.M301976200

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