Wikidata

(Q21116066)

English

Interleukin 6 signal transducer

mammalian protein found in Homo sapiens

  • Interleukin-6 signal transducer
  • gp130
  • gp130, oncostatin M receptor
  • IL-6R subunit beta
  • interleukin receptor beta chain
  • interleukin-6 receptor subunit beta
  • membrane glycoprotein gp130
  • gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
  • membrane glycoprotein 130
  • IL-6 receptor subunit beta
  • IL6ST
  • CDw130
  • oncostatin-M receptor subunit alpha
  • CD130 antigen
  • Cytokine Receptor gp130
In more languages

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
The N-terminal cytokine binding domain of LIFR is required for CNTF binding and signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Detection of direct binding of human herpesvirus 8-encoded interleukin-6 (vIL-6) to both gp130 and IL-6 receptor (IL-6R) and identification of amino acid residues of vIL-6 important for IL-6R-dependent and -independent signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
retrieved
8 April 2019
stated in
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40189
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D050822
subject named as
Cytokine Receptor gp130
0 references
DeCS ID
51128
0 references
Freebase ID
/m/0271f_0
0 references
 
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