(Q37554449)

21 August 2017

Biochemical and functional analyses of gp130 mutants unveil JAK1 as a novel therapeutic target in human inflammatory hepatocellular adenoma (English)

1 reference

Interleukin 6 signal transducer

21 August 2017

0 references

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

18

Jessica Zucman-Rossi

0 references

Paulette Bioulac-Sage

5

Paulette Bioulac-Sage

0 references

Camilla Pilati

Camilla Pilati

2

0 references

Valérie Paradis

Valérie Paradis

7

0 references

Armelle Bardier-Dupas

12

Armelle Bardier-Dupas

1 reference

21 August 2017

11

Catherine Guettier

1 reference

21 August 2017

Karine Poussin

1

1 reference

21 August 2017

Gabrielle Couchy

3

1 reference

21 August 2017

Julien Calderaro

4

1 reference

21 August 2017

Yannick Bacq

6

1 reference

21 August 2017

Emmanuelle Leteurtre

8

1 reference

21 August 2017

Nathalie Sturm

9

1 reference

21 August 2017

Jeanne Ramos

10

1 reference

21 August 2017

Anais Boulai

13

1 reference

21 August 2017

Dominique Wendum

14

1 reference

21 August 2017

Janick Selves

15

1 reference

21 August 2017

Tina Izard

16

1 reference

21 August 2017

Jean-Charles Nault

17

1 reference

21 August 2017

1 December 2013

1 reference

21 August 2017

1 reference

21 August 2017

2

1 reference

21 August 2017

12

1 reference

21 August 2017

e27090

1 reference

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

21 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Src kinase inhibitors: an emerging therapeutic treatment option for prostate cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

STATs in cancer inflammation and immunity: a leading role for STAT3

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Signal transducer and activator of transcription proteins in leukemias.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Bi-allelic inactivation of TCF1 in hepatic adenomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Interleukin 6 and liver regeneration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Crystal structure of a cytokine-binding region of gp130.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Hepatocellular benign tumors-from molecular classification to personalized clinical care

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Dynamics and non-canonical aspects of JAK/STAT signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Revisiting the pathology of resected benign hepatocellular nodules using new immunohistochemical markers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Next-generation sequencing identified new oncogenes and tumor suppressor genes in human hepatic tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

gp130 activation is regulated by D2-D3 interdomain connectivity.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3913689

Ruxolitinib for myelofibrosis.

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FONCI.27090

Genotype–phenotype correlation in hepatocellular adenoma: New classification and relationship with HCC

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FONCI.27090

Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience

21 January 2018

1 reference

12 December 2020

GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation

1 reference

12 December 2020

Synchronous hepatocellular carcinoma and Castleman's disease: the role of the interleukin-6-signaling pathway

1 reference

12 December 2020

Different epitopes are required for gp130 activation by interleukin-6, oncostatin M and leukemia inhibitory factor

1 reference

12 December 2020

Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry

1 reference

12 December 2020

Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation

1 reference

12 December 2020

Identifiers

DOI

10.4161/ONCI.27090

1 reference

release_uskj6yekm5f4to4xnyxnomtfjm

21 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uskj6yekm5f4to4xnyxnomtfjm

24 November 2022

mapped directly with Wikidata item

1 reference

21 August 2017

1 reference