(Q42141408)

English

Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling

scientific article published on April 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

0 references

1 reference

based on heuristic

inferred from title

hepatocellular adenoma

1 reference

based on heuristic

inferred from title

Christoph Garbers

7

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

object named as

Elena Volpi

3

0 references

Stefan Rose-John

object named as

Stefan Rose-John

8

0 references

author name string

Jan Sommer

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Timo Effenberger

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Georg H Waetzig

4

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Marten Bernhardt

5

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Jan Suthaus

6

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Doreen M Floss

9

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Jürgen Scheller

10

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

language of work or name

0 references

publication date

1 April 2012

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

287

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

17

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

13743-13751

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Forced homo- and heterodimerization of all gp130-type receptor complexes leads to constitutive ligand-independent signaling and cytokine-independent growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Autocrine IL-6 signaling: a key event in tumorigenesis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

gp130 dimerization in the absence of ligand: preformed cytokine receptor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Stat proteins and oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

29 May 2018

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340202

17 August 2018

Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new link between cancer and inflammation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two different epitopes of the signal transducer gp130 sequentially cooperate on IL-6-induced receptor activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive activation of STAT3 is associated with the acquisition of an interleukin 6-independent phenotype by murine plasmacytomas and hybridomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22523320

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.349167

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

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