(Q24297991)

Interleukin 6 signal transducer

1 reference

Ciliary neurotrophic factor receptor

1 reference

Ciliary neurotrophic factor

1 reference

Interleukin 6

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LIF interleukin 6 family cytokine

1 reference

LIF receptor subunit alpha

1 reference

leukemia inhibitory factor receptor activity

1 reference

6

Joachim Grötzinger

Joachim

Grötzinger

1 reference

9 December 2023

Stefan Rose-John

7

Stefan

Rose-John

1 reference

9 December 2023

8

Karl-Josef Kallen

Karl-Josef

Kallen

1 reference

9 December 2023

Björn Schuster

1

Björn

Schuster

1 reference

9 December 2023

Marina Kovaleva

2

Marina

Kovaleva

1 reference

9 December 2023

Yi Sun

3

Yi

Sun

1 reference

9 December 2023

Petra Regenhard

4

Petra

Regenhard

1 reference

9 December 2023

Vance Matthews

5

Vance

Journal of Biological Chemistry

Matthews

1 reference

9 December 2023

language of work or name

English

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publication date

14 March 2003

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published in

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volume

278

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page(s)

9528-35

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issue

11

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cites work

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Signaling of the cardiotrophin-1 receptor. Evidence for a third receptor component.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Gp130 and the interleukin-6 family of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor enhances the survival of Purkinje cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Disruption of the CNTF gene results in motor neuron degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Suckling defect in mice lacking the soluble haemopoietin receptor NR6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

A null mutation in the human CNTF gene is not causally related to neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Association of a null mutation in the CNTF gene with early onset of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Centrally mediated inhibition of local inflammation by ciliary neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Circumventing leptin resistance for weight control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Toxicity and tolerability of recombinant human ciliary neurotrophic factor in patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Ciliary neurotrophic factor induces acute-phase protein expression in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

The upper cytokine-binding module and the Ig-like domain of the leukaemia inhibitory factor (LIF) receptor are sufficient for a functional LIF receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

WHAT IF: a molecular modeling and drug design program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

The membrane proximal cytokine receptor domain of the human interleukin-6 receptor is sufficient for ligand binding but not for gp130 association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Soluble receptors for cytokines and growth factors: generation and biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Two-Point Calibration of Circular Dichrometer with d-10-Camphorsulfonic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Ciliary neurotrophic factor regulates fibrinogen gene expression in hepatocytes by binding to the interleukin-6 receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Ciliary neurotrophic factor enhances neuronal survival in embryonic rat hippocampal cultures.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Ciliary neurotrophic factor is a regulator of muscular strength in aging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021

Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210044200

7 January 2021