(Q34698039)

English

Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Christiane Stuhlmann-Laeisz

1

object named as

Christiane Stuhlmann-Laeisz

0 references

Michael S. Samuel

object named as

Michael Samuel

8

0 references

object named as

Jutta Eichler

6

0 references

Ursula Klingmüller

object named as

Ursula Klingmüller

7

0 references

object named as

Matthias Ernst

9

0 references

Stefan Rose-John

object named as

Stefan Rose-John

10

0 references

author name string

Christiane Stuhlmann-Laeisz

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Sigrid Lang

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Athena Chalaris

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Paliga Krzysztof

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Sudarman Enge

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Jürgen Scheller

11

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

publication date

19 April 2006

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2986-2995

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Inhibition of gp130 signaling in breast cancer blocks constitutive activation of Stat3 and inhibits in vivo malignancy

1 reference

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7 July 2018

Constitutive activation of gp130 leads to neuroendocrine differentiation in vitro and in vivo

1 reference

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Selection of genetically modified cell population using hapten-specific antibody/receptor chimera

1 reference

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

1 reference

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The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane

1 reference

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Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells

1 reference

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Stat proteins and oncogenesis

1 reference

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Enhanced transgene expression in primitive hematopoietic progenitor cells and embryonic stem cells efficiently transduced by optimized retroviral hybrid vectors.

1 reference

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Dimerizer-induced proliferation of genetically modified hepatocytes

1 reference

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Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

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Receptor dimerization in GH and erythropoietin action--it takes two to tango, but how?

1 reference

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7 July 2018

Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Importance of the membrane-proximal extracellular domains for activation of the signal transducer glycoprotein 130.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Stat3 as an oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Signaling of type II oncostatin M receptor

1 reference

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7 July 2018

Interleukin-6: structure-function relationships.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Gp130 and the interleukin-6 family of cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Functional replacement of cytokine receptor extracellular domains by leucine zippers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

IL-6 cytokine family and signal transduction: a model of the cytokine system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

7 July 2018

Leucine zipper dimerized bivalent and bispecific scFv antibodies from a semi-synthetic antibody phage display library

1 reference

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7 July 2018

Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

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Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor

1 reference

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Functional and biochemical association of Hck with the LIF/IL-6 receptor signal transducing subunit gp130 in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

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Soluble receptors for cytokines and growth factors: generation and biological function

1 reference

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The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

1 reference

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Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA

1 reference

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Transcriptional activation by tetracyclines in mammalian cells

1 reference

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7 July 2018

Signaling mechanisms through cytokine receptors that share signal transducing receptor components

1 reference

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Sequential mutations in the interleukin-3 (IL3)/granulocyte-macrophage colony-stimulating factor/IL5 receptor beta-subunit genes are necessary for the complete conversion to growth autonomy mediated by a truncated beta C subunit

1 reference

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Interleukin-6 family of cytokines and gp130

1 reference

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1 reference

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1 reference

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

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Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

1 reference

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Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1 reference

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Preferential heterodimer formation by isolated leucine zippers from fos and jun

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483035

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1 reference

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Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

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Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

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based on heuristic

inferred from PubMed ID database lookup

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythropoietin receptor activation by a ligand-induced conformation change

1 reference

https://pubmed.ncbi.nlm.nih.gov/16624864

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E05-12-1129

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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