(Q24301560)

Phosphodiesterase 4B

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Phosphodiesterase 4D

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T cell receptor signaling pathway

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author name string

Daniel Peter

1

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S L Catherine Jin

2

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Marco Conti

3

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Armin Hatzelmann

4

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Christof Zitt

Knockdown of C-terminal Src kinase by siRNA-mediated RNA interference augments T cell receptor signaling in mature T cells

5

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language of work or name

English

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publication date

15 April 2007

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published in

Journal of Immunology

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volume

178

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page(s)

4820-31

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issue

8

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cites work

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

cAMP accumulation in T-cells inhibits anti-CD3 monoclonal antibody-induced actin polymerization

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

New non-viral method for gene transfer into primary cells.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

In vitro PKA phosphorylation-mediated human PDE4A4 activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Phosphodiesterase profiles of highly purified human peripheral blood leukocyte populations from normal and atopic individuals: a comparative study

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Immunosuppressive and anti-inflammatory effects of cyclic AMP phosphodiesterase (PDE) type 4 inhibitors

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Protein kinase A-dependent activation of PDE4 (cAMP-specific cyclic nucleotide phosphodiesterase) in cultured bovine vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

CD4+ T-cell memory, CD45R subsets and the persistence of antigen--a unifying concept.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Molecular mechanisms for protein kinase A-mediated modulation of immune function

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

T-cell antigen receptor genes and T-cell recognition

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Suppression of human inflammatory cell function by subtype-selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Identification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjects

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Phosphodiesterase isoenzyme families in human osteoarthritis chondrocytes--functional importance of phosphodiesterase 4.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Induction of the cyclic nucleotide phosphodiesterase PDE4B is essential for LPS-activated TNF-alpha responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Mobility of the human T lymphocyte surface molecules CD3, CD4, and CD8: regulation by a cAMP-dependent pathway

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

GATA-3 in human T cell helper type 2 development

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

PDE4D plays a critical role in the control of airway smooth muscle contraction

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Characterization of the rolipram-sensitive, cyclic AMP-specific phosphodiesterases: identification and differential expression of immunologically distinct forms in the rat brain

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

CD3- and CD28-dependent induction of PDE7 required for T cell activation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Regulation of T-Cell Activation by Phosphodiesterase 4B2 Requires Its Dynamic Redistribution during Immunological Synapse Formation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Negative regulation of immunoreceptor signaling

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Mediators of Inflammation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Prognostic factors in childhood intracranial ependymomas: the role of age and tumor location.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells.

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

PDE isoenzymes as targets for anti-asthma drugs

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021

Specific role of phosphodiesterase 4B in lipopolysaccharide-induced signaling in mouse macrophages

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.178.8.4820

7 January 2021