(Q24302479)

IRE1-mediated unfolded protein response

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Han-Jou Chen

1

0 references

Georgia Anagnostou

2

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Andrea Chai

3

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James Withers

4

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Alex Morris

5

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Jason Adhikaree

6

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Giuseppa Pennetta

7

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Jackie S de Belleroche

Journal of Biological Chemistry

8

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language of work or name

English

0 references

publication date

17 December 2010

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published in

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volume

285

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issue

51

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page(s)

40266-81

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3001007/fullTextXML

inferred from PubMed Central ID database lookup

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Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

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Structural requirements for VAP-B oligomerization and their implication in amyotrophic lateral sclerosis-associated VAP-B(P56S) neurotoxicity.

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ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

27 September 2017

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27 September 2017

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VAPB interacts with and modulates the activity of ATF6.

27 September 2017

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hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction

27 September 2017

1 reference

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Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

27 September 2017

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27 September 2017

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Ceramide transfer protein function is essential for normal oxidative stress response and lifespan

27 September 2017

1 reference

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Unfolded protein response in Drosophila: why another model can make it fly.

27 September 2017

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Molecular biology of amyotrophic lateral sclerosis: insights from genetics

27 September 2017

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Structural basis of FFAT motif-mediated ER targeting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001007

Enzymes of sphingolipid metabolism in Drosophila melanogaster

27 September 2017

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Modulation of neurodegeneration by molecular chaperones

27 September 2017

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Analysis of conditional paralytic mutants in Drosophila sarco-endoplasmic reticulum calcium ATPase reveals novel mechanisms for regulating membrane excitability

27 September 2017

1 reference

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Drosophila VAP-33A directs bouton formation at neuromuscular junctions in a dosage-dependent manner

27 September 2017

1 reference

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Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum.

27 September 2017

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ERG30, a VAP-33-related protein, functions in protein transport mediated by COPI vesicles

27 September 2017

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Regulation of synapse structure and function by the Drosophila tumor suppressor gene dlg

27 September 2017

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Synapse maturation and structural plasticity at Drosophila neuromuscular junctions

27 September 2017

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27 September 2017

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Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis

30 May 2018

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Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system.

30 May 2018

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Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia.

30 May 2018

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New VAPB deletion variant and exclusion of VAPB mutations in familial ALS.

21 January 2018

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Patterns of inheritance in familial ALS.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.161398

Vesicle associated membrane protein B (VAPB) is decreased in ALS spinal cord.

21 January 2018

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A transgenic mouse model for monitoring endoplasmic reticulum stress

21 January 2018

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

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Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

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Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

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Spinal anterior horn cells in sporadic amyotrophic lateral sclerosis show ribosomal detachment from, and cisternal distention of the rough endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.161398

Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M110.161398

Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.161398

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

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Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

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Hsp70 dynamics in vivo: effect of heat shock and protein aggregation.

21 January 2018

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Nuclear and nucleolar localization of the 72,000-dalton heat shock protein in heat-shocked mammalian cells

21 January 2018

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12 December 2020

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

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12 December 2020

SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations

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12 December 2020

Dyslipidemia is a protective factor in amyotrophic lateral sclerosis

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12 December 2020