(Q24305559)

2

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Matthew D Gray

3

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Jae Wan Lee

4

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Cayetano von Kobbe

5

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Nicolas H Thoma

6

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Raichal P Kureekattil

7

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Mark K Kenny

8

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Robert M Brosh

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

19 August 2005

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published in

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volume

280

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issue

33

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page(s)

29494-505

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cites work

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RecQ helicases: caretakers of the genome

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A putative nucleic acid-binding domain in Bloom's and Werner's syndrome helicases

21 January 2018

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Roles of the Werner syndrome protein in pathways required for maintenance of genome stability

21 January 2018

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A nucleolar targeting sequence in the Werner syndrome protein resides within residues 949-1092.

21 January 2018

1 reference

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Werner syndrome protein contains three structure-specific DNA binding domains

21 January 2018

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Positional cloning of the Werner's syndrome gene

21 January 2018

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The Werner syndrome protein is involved in RNA polymerase II transcription

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Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

21 January 2018

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The Werner syndrome protein is a DNA helicase

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Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

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DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

21 January 2018

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Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein

21 January 2018

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Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

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Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

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The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity

21 January 2018

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Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

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Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

21 January 2018

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Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

21 January 2018

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

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WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

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Oligomeric ring structure of the Bloom's syndrome helicase

21 January 2018

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The Bloom's syndrome gene product interacts with topoisomerase III

21 January 2018

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Dissection of functional domains of the human DNA replication protein complex replication protein A.

21 January 2018

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Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

21 January 2018

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Structural analysis of human replication protein A. Mapping functional domains of the 70-kDa subunit

21 January 2018

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Characterization and mutational analysis of the RecQ core of the bloom syndrome protein

21 January 2018

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Replication focus-forming activity 1 and the Werner syndrome gene product

21 January 2018

1 reference

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Evidence for a replication function of FFA-1, the Xenopus orthologue of Werner syndrome protein

21 January 2018

1 reference

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Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker

21 January 2018

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Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

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Asymmetry of DNA replication fork progression in Werner's syndrome

21 January 2018

1 reference

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Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Molecular genetics of Bloom's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200

Human diseases deficient in RecQ helicases

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500653200