(Q24306398)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

Furin, paired basic amino acid cleaving enzyme

17 November 2019

main subject

1 reference

ADAM metallopeptidase with thrombospondin type 1 motif 4

GOA release 2020-03-11

1 reference

regulation of endopeptidase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Ping Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Micky Tortorella

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Kristen England

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Gary Thomas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

Elizabeth C Arner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

language of work or name

English

0 references

publication date

26 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

volume

279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

page(s)

15434-15440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

17 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Expression and regulation of aggrecanase in arthritis: the role of TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Aggrecanase-mediated cartilage degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Intracellular activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Activation of the proteolytic activity of ADAMTS4 (aggrecanase-1) by C-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Autocatalytic cleavage of ADAMTS-4 (Aggrecanase-1) reveals multiple glycosaminoglycan-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Curbing activation: proprotein convertases in homeostasis and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Processing of beta-secretase by furin and other members of the proprotein convertase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Potent and selective aggrecanase inhibitors containing cyclic P1 substituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

The PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Functional characterization of MT3-MMP in transfected MDCK cells: progelatinase A activation and tubulogenesis in 3-D collagen lattice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Endoprotease activities other than furin and PACE4 with a role in processing of HIV-I gp160 glycoproteins in CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Processing of wild-type and mutant proinsulin-like growth factor-IA by subtilisin-related proprotein convertases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

The Notch1 receptor is cleaved constitutively by a furin-like convertase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Furin at the cutting edge: from protein traffic to embryogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

Furin interacts with proMT1-MMP and integrin alphaV at specialized domains of renal cell plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

inferred from DOI database lookup

7 January 2021

based on heuristic

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312797200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M312797200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14744861%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017