(Q24307395)

English

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15489227%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription (English)

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4 January 2020

0 references

TLE family member 5, transcriptional modulator

1 reference

GOA release 2020-03-11

RELA proto-oncogene, NF-kB subunit

1 reference

GOA release 2020-03-11

TATA-box binding protein associated factor 9

1 reference

GOA release 2020-03-11

response to interleukin-1

1 reference

GOA release 2020-03-11

phosphorylation

1 reference

based on heuristic

inferred from title

Lienhard Schmitz

3

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Europe PubMed Central

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4 January 2020

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4 January 2020

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Holger Buss

1

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4 January 2020

Anneke Dörrie

2

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4 January 2020

Elke Hoffmann

4

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4 January 2020

Klaus Resch

5

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4 January 2020

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15 October 2004

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4 January 2020

Journal of Biological Chemistry

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4 January 2020

279

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4 January 2020

53

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4 January 2020

55633-55643

1 reference

Europe PubMed Central

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4 January 2020

NF-kappaB: a multifaceted transcription factor regulated at several levels

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Missing pieces in the NF-kappaB puzzle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein modelling for all

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of proinflammatory cytokine-induced biphasic NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

NAK is an IkappaB kinase-activating kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB regulation in the immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Shaping the nuclear action of NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-1 activates a novel protein kinase that phosphorylates the epidermal-growth-factor receptor peptide T669.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

S6 kinase in quiescent Swiss mouse 3T3 cells is activated by phosphorylation in response to serum treatment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical structural elements and multitarget protein interactions of the transcriptional activator AF-1 of hepatocyte nuclear factor 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Divergent hTAFII31-binding motifs hidden in activation domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

The NF-kappa b repressing factor is involved in basal repression and interleukin (IL)-1-induced activation of IL-8 transcription by binding to a conserved NF-kappa b-flanking sequence element.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

IKKi/IKKϵ Plays a Key Role in Integrating Signals Induced by Pro-inflammatory Stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Induced alpha helix in the VP16 activation domain upon binding to a human TAF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative analysis of T-cell costimulation and CD43 activation reveals novel signaling pathways and target genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409825200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M409825200

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15489227%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15489227%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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