(Q43815830)

English

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

scientific article published on 3 December 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 November 2017

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

phosphorylation

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1 reference

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inferred from title

Hiroaki Sakurai

4

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

author name string

Nywana Sizemore

1

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Natalia Lerner

2

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Nicole Dombrowski

3

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

George R Stark

5

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Europe PubMed Central

PubMed publication ID

27 November 2017

language of work or name

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publication date

3 December 2001

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Europe PubMed Central

PubMed publication ID

27 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

27 November 2017

277

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Europe PubMed Central

PubMed publication ID

27 November 2017

6

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Europe PubMed Central

PubMed publication ID

27 November 2017

3863-3869

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

The Akt proto-oncogene links Ras to Pak and cell survival signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Activation of transcription factor NF-kappaB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Inhibition of JNK activation through NF-kappaB target genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Tumor Necrosis Factor-α Activation of NF-κB Requires the Phosphorylation of Ser-471 in the Transactivation Domain of c-Rel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110572200

21 January 2018

Identifiers

10.1074/JBC.M110572200

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 November 2017

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