(Q40805561)

23 September 2017

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity (English)

1 reference

23 September 2017

3

J E Dixon

1 reference

23 September 2017

J A Gustin

1

1 reference

23 September 2017

T Maehama

series ordinal

2

1 reference

23 September 2017

D B Donner

series ordinal

4

1 reference

23 September 2017

language of work or name

English

0 references

publication date

16 May 2001

1 reference

Journal of Biological Chemistry

23 September 2017

1 reference

23 September 2017

276

1 reference

23 September 2017

27740-27744

1 reference

23 September 2017

29

1 reference

TNF, apoptosis and autoimmunity: a common thread?

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

TNF-alpha and insulin resistance: summary and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Tumor necrosis factor receptor and Fas signaling mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

NF-kappa B: ten years after

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Activation of phosphatidylinositol 3-kinase by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Akt signaling: linking membrane events to life and death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Tumor necrosis factor-alpha induces distinctive NF-kappa B signaling within human dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Somatic deletion mapping on chromosome 10 and sequence analysis of PTEN/MMAC1 point to the 10q25-26 region as the primary target in low-grade and high-grade gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

PTEN: sometimes taking it off can be better than putting it on.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Role of the protein kinase C lambda/iota isoform in nuclear factor-kappaB activation by interleukin-1beta or tumor necrosis factor-alpha: cell type specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

The role of PI 3-kinase in insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M102559200

21 January 2018

Identifiers

DOI

10.1074/JBC.M102559200

1 reference

23 September 2017

1 reference