(Q24307591)

positive regulation of transcription by RNA polymerase II

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SMAD family member 4

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SMAD family member 1

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author name string

Wenjun Zhang

1

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Tatiana A Yatskievych

2

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Xu Cao

3

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Parker B Antin

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

22 November 2002

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published in

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volume

277

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issue

47

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page(s)

45435-41

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cites work

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Bone morphogenetic proteins: multifunctional regulators of vertebrate development

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OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

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TGF-beta signal transduction

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Smads as transcriptional co-modulators

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

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Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm

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Characterization of a bone morphogenetic protein-responsive Smad-binding element

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Smad6 is a Smad1/5-induced smad inhibitor. Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter

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Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

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Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene

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Interaction of Smad complexes with tripartite DNA-binding sites

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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Human Smad3 and Smad4 are sequence-specific transcription activators

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Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling

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Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

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Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

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ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

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Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

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Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo

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Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes.

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BMP signaling is required for heart formation in vertebrates

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BMP2 is required for early heart development during a distinct time period.

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BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos.

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Liver specification and early morphogenesis

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Hex expression suggests a role in the development and function of organs derived from foregut endoderm.

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The XHex homeobox gene is expressed during development of the vascular endothelium: overexpression leads to an increase in vascular endothelial cell number

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Expression of the homebox gene Hex during early stages of chick embryo development

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Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage

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An efficient method for generation and subcloning of tandemly repeated DNA sequences with defined length, orientation and spacing

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Genomic organization and promoter analysis of a mouse homeobox gene, Hex.

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Molecular genetics of early liver development

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Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.

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Identification of a novel vertebrate homeobox gene expressed in haematopoietic cells

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Nkx-2.5 gene induction in mice is mediated by a Smad consensus regulatory region.

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Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

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Determinants of specificity in TGF-beta signal transduction.

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Distinct Enhancer Elements Control Hex Expression during Gastrulation and Early Organogenesis

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Smad1 and Smad4 are components of the bone morphogenetic protein-4 (BMP-4)-induced transcription complex of the Xvent-2B promoter

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Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators

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A role for bone morphogenetic proteins in the induction of cardiac myogenesis

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Regulation of avian cardiac myogenesis by activin/TGFbeta and bone morphogenetic proteins

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Initiation of mammalian liver development from endoderm by fibroblast growth factors

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Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperative

21 January 2018

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Evidence that fibroblast growth factors 1 and 4 participate in regulation of cardiogenesis

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