(Q24308849)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0071666

Slit guidance ligand 2

1 reference

negative regulation of retinal ganglion cell axon guidance

1 reference

Slit Dmel_CG43758

1 reference

Roundabout 1 Dmel_CG13521

1 reference

Laure Strochlic

4

0 references

Jason A. Howitt

Jason A Howitt

6

0 references

Michael Piper

Michael Piper

2

0 references

Christine Holt

Christine E Holt

10

0 references

Erhard Hohenester

11

Erhard Hohenester

0 references

Sadaf-Ahmahni Hussain

1

Sadaf-Ahmahni Hussain

0 references

author name string

Noémi Fukuhara

3

0 references

Gian Cho

5

0 references

Yassir Ahmed

7

0 references

Andrew K Powell

8

0 references

Jeremy E Turnbull

Journal of Biological Chemistry

9

0 references

language of work or name

English

0 references

publication date

22 December 2006

0 references

published in

0 references

volume

281

0 references

page(s)

39693-8

0 references

issue

51

0 references

cites work

Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Robo1 and Robo2 are homophilic binding molecules that promote axonal growth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Characterization of Slit protein interactions with glypican-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Robo4 is a vascular-specific receptor that inhibits endothelial migration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Molecular mechanisms of axon guidance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Robo4 signaling in endothelial cells implies attraction guidance mechanisms.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Common mechanisms of nerve and blood vessel wiring

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

The versatile roles of "axon guidance" cues in tissue morphogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Syndecans: proteoglycan regulators of cell-surface microdomains?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Signalling mechanisms mediating neuronal responses to guidance cues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Slit proteins: key regulators of axon guidance, axonal branching, and cell migration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance.

27 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609384200

Syndecan regulates cell migration and axon guidance in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609384200

Axon sorting in the optic tract requires HSPG synthesis by ext2 (dackel) and extl3 (boxer).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609384200

Differential sulfations and epimerization define heparan sulfate specificity in nervous system development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609384200

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609384200

Specific heparan sulfate structures involved in retinal axon targeting.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3680705

An essential heparin-binding domain in the fibroblast growth factor receptor kinase

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17062560

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17062560