(Q24310435)

English

Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism

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scholarly article

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Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism (English)

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Growth factor independent 1B transcriptional repressor

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GOA release 2020-03-11

Growth factor independent 1 transcriptional repressor

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GOA release 2020-03-11

negative regulation of transcription, DNA-templated

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GOA release 2020-03-11

H. Leighton Grimes

4

object named as

H Leighton Grimes

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author name string

Laura McGhee

1

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Josh Bryan

2

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Liza Elliott

3

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Avedis Kazanjian

5

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J Nathan Davis

6

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Shari Meyers

7

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language of work or name

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publication date

1 August 2003

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Journal of Cellular Biochemistry

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89

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5

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1005-18

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Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia

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7 January 2021

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inferred from DOI database lookup

Gsh-1: a novel murine homeobox gene expressed in the central nervous system

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https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylases, transcriptional control, and cancer

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https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1 reference

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based on heuristic

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

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based on heuristic

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Snail/slug family of repressors: slowly going into the fast lane of development and cancer

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

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based on heuristic

inferred from DOI database lookup

The ETO (MTG8) gene family

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https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

ETO-2, a new member of the ETO-family of nuclear proteins.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear import and subnuclear localization of the proto-oncoprotein ETO (MTG8)

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

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based on heuristic

inferred from DOI database lookup

High levels of the onco-protein Gfi-1 accelerate T-cell proliferation and inhibit activation induced T-cell death in Jurkat T-cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death

1 reference

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based on heuristic

inferred from DOI database lookup

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple regions of ETO cooperate in transcriptional repression

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

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based on heuristic

inferred from DOI database lookup

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

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based on heuristic

inferred from DOI database lookup

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Human Slug is a repressor that localizes to sites of active transcription

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

1 reference

https://api.crossref.org/works/10.1002%2FJCB.10548

7 January 2021

based on heuristic

inferred from DOI database lookup

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/JCB.10548

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release_ieauiqdi2rfsdodud5ra3ci6ne

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