(Q24312504)

English

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

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scholarly article

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The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins (English)

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GOA release 2020-03-11

cargo receptor activity

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GOA release 2020-03-11

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based on heuristic

inferred from title

membrane protein

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Renata Kozyraki

object named as

R Kozyraki

2

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author name string

S K Moestrup

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M Kristiansen

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J H Kaysen

4

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H H Rasmussen

5

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D Brault

6

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F Pontillon

7

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F O Goda

8

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E I Christensen

9

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T G Hammond

10

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P J Verroust

11

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language of work or name

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publication date

27 February 1998

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Journal of Biological Chemistry

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273

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9

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5235-42

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39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

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RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors

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Crystallization and preliminary X-ray diffraction studies of aSFP, a bovine seminal plasma protein with a single CUB domain architecture.

1 reference

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Cell physiology of the rat visceral yolk sac: a study of pinocytosis and lysosome function

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The CUB domain. A widespread module in developmentally regulated proteins

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Purification and characterization of rabbit transcobalamin II.

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Characterization of carbohydrates in the alpha 2-macroglobulin receptor

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Crystallization and preliminary X-ray diffraction analysis of boar seminal plasma spermadhesin PSP-I/PSP-II, a heterodimer of two CUB domains

1 reference

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Decreased activity of intestinal and urinary intrinsic factor receptor in Gräsbeck-Imerslund disease [corrected]

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LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation

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Isolation and characterization of heparin- and phosphorylcholine-binding proteins of boar and stallion seminal plasma. Primary structure of porcine pB1.

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Amino-terminal calcium-binding domain of human complement C1.hivin.s mediates the interaction of C1.hivin.r with C1q

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A second serine protease associated with mannan-binding lectin that activates complement

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IGF2 is parentally imprinted in human preimplantation embryos.

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Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells

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Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

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Defective forebrain development in mice lacking gp330/megalin

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Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis

1 reference

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Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein

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Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

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Isolation, partial characterization, and localization of a rat renal tubular glycoprotein antigen. Antibody-induced birth defects

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Characterization of a 280-kD protein restricted to the coated pits of the renal brush border and the epithelial cells of the yolk sac. Teratogenic effect of the specific monoclonal antibodies

1 reference

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Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

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Selective vitamin B12 malabsorption and proteinuria in young people. A syndrome.

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Solubilization, Partial Purification and Radioassay for the Intrinsic Factor Receptor from the Ileal Mucosa

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Analysis of the structural organization and thermal stability of two spermadhesins. Calorimetric, circular dichroic and Fourier-transform infrared spectroscopic studies.

1 reference

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Identification of a macromolecular factor in the ileum which binds intrinsic factor and immunologic identification of intrinsic factor in ileal extracts

1 reference

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Cobalamin malabsorption in three siblings due to an abnormal intrinsic factor that is markedly susceptible to acid and proteolysis

1 reference

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based on heuristic

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Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

1 reference

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Interaction of Non-Aggregated Boar AWN-1 and AQN-3 with Phospholipid Matrices. A Model for Coating of Spermadhesins to the Sperm Surface

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inferred from DOI database lookup

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10.1074/JBC.273.9.5235

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