(Q24314837)

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Megumi Sado

1

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Yuki Yamasaki

2

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Tomoyuki Iwanaga

3

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Yasushi Onaka

4

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Tatsuki Ibuki

5

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Shigeki Nishihara

6

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Hiroshi Mizuguchi

7

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Hiroshi Momota

8

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Ryuichi Kishibuchi

9

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Tetsuya Hashimoto

10

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Daisuke Wada

11

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Hisashi Kitagawa

12

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Takeshi K Watanabe

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

13

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language of work or name

English

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publication date

27 February 2009

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published in

Brain Research

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volume

1257

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page(s)

16-24

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

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Lack of nigrostriatal pathology in a rat model of proteasome inhibition.

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Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice

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Altered proteasomal function in sporadic Parkinson's disease

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Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease.

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

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7 January 2021

Discordance of UPR signaling by ATF6 and Ire1p-XBP1 with levels of target transcripts

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Activation of the unfolded protein response in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

A trip to the ER: coping with stress

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

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7 January 2021

Mitochondrial complex I deficiency in Parkinson's disease

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7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

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7 January 2021

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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7 January 2021

ER stress and neurodegenerative diseases

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7 January 2021

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

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7 January 2021

Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

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7 January 2021

The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease

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Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity

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7 January 2021

MPP+ induces the endoplasmic reticulum stress response in rabbit brain involving activation of the ATF-6 and NF-kappaB signaling pathways

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

ER stress and diseases.

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Etiology and pathogenesis of Parkinson's disease

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Salsolinol causing parkinsonism activates endoplasmic reticulum-stress signaling pathways in human dopaminergic SK-N-SH cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

The pathogenesis of cell death in Parkinson's disease

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https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BRAINRES.2008.11.104

7 January 2021