(Q24316314)

GOA release 2020-03-11

1 reference

Carol MacKintosh

4

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Christopher G. Proud

object named as

Christopher G Proud

5

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author name string

Bruno D Fonseca

1

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Ewan M Smith

2

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Vivian H-Y Lee

Journal of Biological Chemistry

3

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language of work or name

English

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publication date

24 August 2007

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published in

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volume

282

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issue

34

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page(s)

24514-24

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cites work

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Identification of a conserved motif required for mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Regulation of the 14-3-3-binding protein p39 by growth factors and nutrients in rat PC12 pheochromocytoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Simian virus 40 small tumor antigen activates AKT and telomerase and induces anchorage-independent growth of human epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Analysis of insulin receptor phosphorylation sites in intact rat liver cells by two-dimensional phosphopeptide mapping. Predominance of the tris-phosphorylated form of the kinase domain after stimulation by insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Dephosphorylation of the inhibitory phosphorylation site S287 in Xenopus Cdc25C by protein phosphatase-2A is inhibited by 14-3-3 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Protein kinase A phosphorylation of human phosphodiesterase 3B promotes 14-3-3 protein binding and inhibits phosphatase-catalyzed inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Rheb binds and regulates the mTOR kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

The 14-3-3 proteins positively regulate rapamycin-sensitive signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Different roles for the TOS and RAIP motifs of the translational regulator protein 4E-BP1 in the association with raptor and phosphorylation by mTOR in the regulation of cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

PRAS40 deregulates apoptosis in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

Neuroprotective role of neurotrophins: relationship between nerve growth factor and apoptotic cell survival pathway after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704406200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704406200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

17604271

1 reference

Consolidated OpenCitations Corpus – April 2017