(Q24322589)

William J McKinstry

11

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Hayley S. Ramshaw

Hayley Ramshaw

7

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Angel F. Lopez

Angel F Lopez

12

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Michael W Parker

Michael W Parker

13

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author name string

Guido Hansen

1

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Timothy R Hercus

2

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Barbara J McClure

3

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Frank C Stomski

4

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Mara Dottore

5

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Jason Powell

6

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Yibin Xu

9

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Mark Guthridge

Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation

10

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language of work or name

English

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publication date

8 August 2008

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published in

Cell

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volume

134

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page(s)

496-507

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issue

3

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Dendritic cells: specialized and regulated antigen processing machines

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccination

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Chronic myelomonocytic leukemia requires granulocyte-macrophage colony-stimulating factor for growth in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Nf1 and Gmcsf interact in myeloid leukemogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Sargramostim for active Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Histidine-367 of the human common beta chain of the receptor is critical for high-affinity binding of human granulocyte-macrophage colony-stimulating factor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

A dominant negative granulocyte-macrophage colony-stimulating factor receptor alpha chain reveals the multimeric structure of the receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three recepto

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

A cell type-specific constitutive point mutant of the common beta-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor alpha-subunit for activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

A Novel Functional Epitope Formed by Domains 1 and 4 of the Human Common β-Subunit Is Involved in Receptor Activation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin 5

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Crucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognition

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Hematopoietic receptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

The JAK/STAT signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Functions of granulocyte-macrophage colony-stimulating factor.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021

Potent CD4+ T cell responses elicited by a bicistronic HIV-1 DNA vaccine expressing gp120 and GM-CSF

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.05.053

7 January 2021