Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q24322747)
Watch
English
Interplay of LRRK2 with chaperone-mediated autophagy
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Interplay of LRRK2 with chaperone-mediated autophagy
(English)
0 references
main subject
autophagy
0 references
molecular chaperones
0 references
author
Ana María Cuervo
series ordinal
13
0 references
Esperanza Arias
object named as
Esperanza Arias
series ordinal
4
0 references
Sheng-Han Kuo
object named as
Sheng-Han Kuo
series ordinal
2
0 references
William T Dauer
object named as
William Dauer
series ordinal
9
0 references
Ángel Raya
object named as
Angel Raya
series ordinal
11
0 references
Dave Soldier
series ordinal
12
object named as
David Sulzer
0 references
author name string
Samantha J Orenstein
series ordinal
1
0 references
Inmaculada Tasset
series ordinal
3
0 references
Hiroshi Koga
series ordinal
5
0 references
Irene Fernandez-Carasa
series ordinal
6
0 references
Etty Cortes
series ordinal
7
0 references
Lawrence S Honig
series ordinal
8
0 references
Antonella Consiglio
series ordinal
10
0 references
language of work or name
English
0 references
publication date
April 2013
0 references
published in
Nature Neuroscience
0 references
volume
16
0 references
issue
4
0 references
page(s)
394-406
0 references
on focus list of Wikimedia project
ScienceSource
0 references
cites work
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Chaperone-mediated autophagy: molecular mechanisms and physiological relevance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Lysosome membrane lipid microdomains: novel regulators of chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
A receptor for the selective uptake and degradation of proteins by lysosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Autophagy fights disease through cellular self-digestion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Alpha-synuclein in Lewy bodies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Chaperone-mediated autophagy markers in Parkinson disease brains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Adapting proteostasis for disease intervention
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
19 March 2017
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
7 April 2017
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
7 April 2017
Clinical and pathological characteristics of LRRK2 G2019S patients with PD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Chaperone-mediated autophagy is required for tumor growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
LRRK2 Parkinson disease mutations enhance its microtubule association.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
A photoconvertible fluorescent reporter to track chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Lysosomal degradation of alpha-synuclein in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Chaperone-mediated autophagy: selectivity pays off.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Methods to monitor chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Consequences of the selective blockage of chaperone-mediated autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Peptide sequences that target cytosolic proteins for lysosomal proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
27 September 2017
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
30 May 2018
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
30 May 2018
Regulation of lamp2a levels in the lysosomal membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
30 May 2018
Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
30 May 2018
Isolation of subcellular organelles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
30 May 2018
In search of an "autophagomometer".
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
29 November 2018
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609872
retrieved
29 November 2018
Blastomycosis of the lung
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23455607
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peptide sequences that target proteins for enhanced degradation during serum withdrawal
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23455607
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective binding and uptake of ribonuclease A and glyceraldehyde-3-phosphate dehydrogenase by isolated rat liver lysosomes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23455607
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neuronal vulnerability, pathogenesis, and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNN.3350
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NN.3350
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747248
Dimensions Publication ID
1030067867
0 references
OpenCitations bibliographic resource ID
747248
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747248
PMC publication ID
3609872
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747248
PubMed publication ID
23455607
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
747248
ResearchGate publication ID
235776642
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit