(Q24322952)

double-strand break repair via homologous recombination

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

Shirley M-H Sy

1

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author name string

Michael S Y Huen

series ordinal

2

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Yongyou Zhu

series ordinal

3

0 references

Junjie Chen

series ordinal

4

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language of work or name

English

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publication date

3 July 2009

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published in

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volume

284

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issue

27

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page(s)

18302-10

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cites work

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

1 reference

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Human CtIP promotes DNA end resection

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Analysis of PALB2/FANCN-associated breast cancer families

19 March 2017

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PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

19 March 2017

1 reference

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

19 March 2017

1 reference

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BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

19 March 2017

1 reference

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BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

19 March 2017

1 reference

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Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Resistance to therapy caused by intragenic deletion in BRCA2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

The DNA damage response: ten years after

19 March 2017

1 reference

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HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability

19 March 2017

1 reference

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MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

19 March 2017

1 reference

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

19 March 2017

1 reference

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Coiled coils: a highly versatile protein folding motif

19 March 2017

1 reference

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DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

PALB2 links BRCA1 and BRCA2 in the DNA-damage response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

The DNA damage response pathways: at the crossroad of protein modifications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

BRCA2: a universal recombinase regulator.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Checking on DNA damage in S phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Structure and function of the double-strand break repair machinery.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Emerging functions of BRCA2 in DNA recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

DNA damage tumor suppressor genes and genomic instability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

BRCA1, BRCA2, and DNA damage response: collision or collusion?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

A recurrent mutation in PALB2 in Finnish cancer families.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2709360

RAD51, BRCA2 and DNA repair: a partial resolution

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19423707