(Q24323295)

GOA release 2020-03-11

author

Xavier Parés

9

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Armando Moro

Armando Moro

4

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Oriol Gallego

Oriol Gallego

3

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Jaume Farrés

Jaume Farrés

8

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Carme Rovira

Carme Rovira

7

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author name string

F Xavier Ruiz

1

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Sergio Porté

2

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Albert Ardèvol

5

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Alberto Del Río-Espínola

Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

6

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language of work or name

English

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publication date

15 December 2011

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published in

Biochemical Journal

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volume

440

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issue

3

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page(s)

335-44

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cites work

1 reference

Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism

20 April 2017

1 reference

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

20 April 2017

1 reference

Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

20 April 2017

1 reference

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia

20 April 2017

1 reference

Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10

20 April 2017

1 reference

Identification of a retinoic acid responsive aldoketoreductase expressed in HL60 leukaemic cells

20 April 2017

1 reference

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function

20 April 2017

1 reference

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution

20 April 2017

1 reference

20 April 2017

1 reference

20 April 2017

1 reference

Overview of retinoid metabolism and function

20 April 2017

1 reference

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

20 April 2017

1 reference

From carrot to clinic: an overview of the retinoic acid signaling pathway

20 April 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Retinoids, retinoic acid receptors, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Medium- and short-chain dehydrogenase/reductase gene and protein families : Medium-chain and short-chain dehydrogenases/reductases in retinoid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

A vertebrate aldo-keto reductase active with retinoids and ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Structure-function of human 3 alpha-hydroxysteroid dehydrogenases: genes and proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Identification of amino acid residues responsible for differences in substrate specificity and inhibitor sensitivity between two human liver dihydrodiol dehydrogenase isoenzymes by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Aldo-keto reductases and bioactivation/detoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Multiplicity of mammalian reductases for xenobiotic carbonyl compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Human aldo-keto reductases: Function, gene regulation, and single nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Steroid hormone transforming aldo-keto reductases and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Induction of neoplastic transformation by ectopic expression of human aldo-keto reductase 1C isoforms in NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Aldo-keto reductases from the AKR1B subfamily: retinoid specificity and control of cellular retinoic acid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

A pitfall of using a second plasmid to determine transfection efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Vitamin E activates CRABP-II gene expression in cultured human fibroblasts, role of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Development of nonsteroidal anti-inflammatory drug analogs and steroid carboxylates selective for human aldo-keto reductase isoforms: potential antineoplastic agents that work independently of cyclooxygenase isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Cis-retinol dehydrogenase: 9-cis-retinol metabolism and its effect on proliferation of human MCF7 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Growth control or terminal differentiation: endogenous production and differential activities of vitamin A metabolites in HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Metabolism of vitamin A affected by prostaglandin F synthase in contractile interstitial cells of bovine lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Expression of a smaller lecithin:retinol acyl transferase transcript and reduced retinol esterification in MCF-7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Understanding retinol metabolism: structure and function of retinol dehydrogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Identification of 9-cis-retinoic acid as a pancreas-specific autacoid that attenuates glucose-stimulated insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dDelta12,14,PGJ2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

7 January 2021

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

7 January 2021

Characterization of the substrate binding site in rat liver 3alpha-hydroxysteroid/dihydrodiol dehydrogenase. The roles of tryptophans in ligand binding and protein fluorescence

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

7 January 2021

Activation of retinoid X receptors induces apoptosis in HL-60 cell lines

1 reference

https://api.crossref.org/works/10.1042%2FBJ20111286

7 January 2021