(Q24336930)

aldo-keto reductase family 1 member C3

GOA release 2020-03-11

1 reference

aldo-keto reductase family 1 member C2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

N Hevir

1

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K Vouk

2

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J Sinkovec

3

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M Ribič-Pucelj

4

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T Lanišnik Rižner

Chemico-biological Interactions

5

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language of work or name

English

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publication date

30 May 2011

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published in

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volume

191

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page(s)

217-26

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issue

1-3

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cites work

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Immunoreactivity of progesterone receptor isoform B and nuclear factor kappa-B as biomarkers for recurrence of ovarian endometriomas.

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Pathogenesis of endometriosis

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Progestins as inhibitors of the human 20-ketosteroid reductases, AKR1C1 and AKR1C3

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Differential expression of genes in eutopic and ectopic endometrium from patients with ovarian endometriosis

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The knockdown of progesterone receptor isoform B (PR-B) promotes proliferation in immortalized endometrial stromal cells

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Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

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Novel estrogen-related genes and potential biomarkers of ovarian endometriosis identified by differential expression analysis

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The dialectic role of progesterone

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AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer

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Deoxycorticosterone inactivation by AKR1C3 in human mineralocorticoid target tissues

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Progesterone resistance in endometriosis: link to failure to metabolize estradiol

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Disturbed estrogen and progesterone action in ovarian endometriosis

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Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

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Estrogen metabolism and action in endometriosis

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Characterization of a monoclonal antibody for human aldo-keto reductase AKR1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase); immunohistochemical detection in breast and prostate

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Selective and potent inhibitors of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone

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Progesterone metabolism in human endometrial stromal and gland cells in culture.

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Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

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17Beta-hydroxysteroid dehydrogenase-2 deficiency and progesterone resistance in endometriosis

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Characterization of binding components for progesterone and 5alpha-pregnane-3,20-dione in the hamster uterus

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Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases

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Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex

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Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action

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Endometriosis: the way forward

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Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis

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Expression of 17beta-hydroxysteroid dehydrogenase type 2 in pelvic endometriosis

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Estrogen metabolizing enzymes in endometrium and endometriosis.

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Androgen receptor and 5alpha-reductase are expressed in pelvic endometriosis.

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The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7.

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The pains of endometriosis

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Steroid 5 alpha-reductase: two genes/two enzymes

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Dominant expression of progesterone receptor form B mRNA in ovarian endometriosis

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

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Characterization of molecular and catalytic properties of intact and truncated human 17beta-hydroxysteroid dehydrogenase type 2 enzymes: intracellular localization of the wild-type enzyme in the endoplasmic reticulum.

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Inflammatory status influences aromatase and steroid receptor expression in endometriosis.

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7 January 2021

Metabolism of Progesterone in Human Proliferative Endometrium1

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Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.

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Progesterone Metabolism in Normal Human Endometrium During the Menstrual Cycle and in Endometrial Carcinoma

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Stromal PRs mediate induction of 17beta-hydroxysteroid dehydrogenase type 2 expression in human endometrial epithelium: a paracrine mechanism for inactivation of E2.

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7 January 2021

Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines

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7 January 2021

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

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7 January 2021

Sequential transformation of 4-androstenedione into dihydrotestosterone in prostate carcinoma (DU-145) cells indicates that 4-androstenedione and not testosterone is the substrate of 5α-reductase

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7 January 2021

Reproductive tissue selective actions of progesterone receptors.

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7 January 2021

Promoter hypermethylation of progesterone receptor isoform B (PR-B) in endometriosis

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7 January 2021