(Q24658019)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Trevor M Penning

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1

Jason E Drury

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

David W Christianson

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

language of work or name

English

0 references

publication date

10 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

30 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

page(s)

19786-19790

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

30 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Structure and catalytic mechanism of human steroid 5β-reductase (AKR1D1)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Crystal Structure of Human Liver 4-3-Ketosteroid 5 -Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Coot: model-building tools for molecular graphics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

The enzymes, regulation, and genetics of bile acid synthesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

The Cambridge Structural Database: a quarter of a million crystal structures and rising

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

7 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Comparative anatomy of the aldo-keto reductase superfamily

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

A robust bulk-solvent correction and anisotropic scaling procedure

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

The influence of finasteride on the development of prostate cancer

25 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Evaluation of men on finasteride

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Steroid 5 alpha-reductase: two genes/two enzymes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

The clinical development of a 5α-reductase inhibitor, finasteride

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2740403

Processing of X-ray diffraction data collected in oscillation mode

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.C109.016931

Structural characterization of polymorphs and molecular complexes of finasteride

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.C109.016931

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

21 January 2018

1 reference

12 December 2020

Analysis of the steric strain in the polypeptide backbone of protein molecules

1 reference

12 December 2020

Treatment with finasteride following radical prostatectomy for prostate cancer

1 reference

12 December 2020

Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride

1 reference

12 December 2020

Differential effect of finasteride on the tissue androgen concentrations in benign prostatic hyperplasia

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.C109.016931

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515843%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference