(Q24337000)

GOA release 2020-03-11

Paired box 6

1 reference

GOA release 2020-03-11

1 reference

Yvan Gosmain

1

0 references

Eric Marthinet

2

0 references

Claire Cheyssac

3

0 references

Audrey Guérardel

4

0 references

Aline Mamin

5

0 references

Liora S Katz

6

0 references

Karim Bouzakri

7

0 references

Jacques Philippe

Journal of Biological Chemistry

8

0 references

language of work or name

English

0 references

publication date

22 October 2010

0 references

published in

0 references

volume

285

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issue

43

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page(s)

33381-93

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cites work

MafB is required for islet beta cell maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

PAX6 mutation as a genetic factor common to aniridia and glucose intolerance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Foxa2 is required for the differentiation of pancreatic alpha-cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Cell-autonomous involvement of Mab21l1 is essential for lens placode development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

PAX-6 in development and evolution

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Regulation of c-maf gene expression by Pax6 in cultured cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Pax-6, a murine paired box gene, is expressed in the developing CNS

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Pax6 regulates the proglucagon processing enzyme PC2 and its chaperone 7B2.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Preferential reduction of beta cells derived from Pax6-MafB pathway in MafB deficient mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

The role of alpha-cell dysregulation in fasting and postprandial hyperglycemia in type 2 diabetes and therapeutic implications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Opposing actions of Arx and Pax4 in endocrine pancreas development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Hepatic nuclear factor-3 (HNF-3 or Foxa2) regulates glucagon gene transcription by binding to the G1 and G2 promoter elements

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Interaction of Maf transcription factors with Pax-6 results in synergistic activation of the glucagon promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Truncation mutations in the transactivation region of PAX6 result in dominant-negative mutants

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Homologous DNA sequences and cellular factors are implicated in the control of glucagon and insulin gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Islet-specific proteins interact with the insulin-response element of the glucagon gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Identification of a novel lymphoid specific octamer binding protein (OTF-2B) by proteolytic clipping bandshift assay (PCBA).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Isolation of glucagon-secreting cell lines by cloning insulinoma cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963382

Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

A case of novel de novo paired box gene 6 (PAX6) mutation with early-onset diabetes mellitus and aniridia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

Neogenesis of beta-cells in adult BETA2/NeuroD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

Autofluorescence-activated cell sorting of pancreatic islet cells: Purification of insulin-containing B-cells according to glucose-induced changes in cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

Genetic determinants of pancreatic epsilon-cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

21 January 2018

1 reference

12 December 2020

Sorting human beta-cells consequent to targeted expression of green fluorescent protein

1 reference

12 December 2020

Cloning and characterization of promoter of the mouse mafB gene

1 reference

12 December 2020

Isolation of rat pancreatic islets by ductal injection of collagenase

1 reference

12 December 2020

The upstream promoter element of the glucagon gene, G1, confers pancreatic alpha cell-specific expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147215

7 January 2021